Mark Walker

TL;DR: Even after fasting, biochemical measurements may still differ in relation to fasting duration and time of day, so it is important to standardize both the period of fasting and the time ofday as much as possible, and make adjustments where necessary.

TL;DR: Longer overnight suppression of lipolysis and lipid oxidation in obese NIDDM lowers fasting blood glucose and HGO and increases peripheral and hepatic sensitivity to insulin in obeseNIDDM patients.

TL;DR: It is concluded that genetic variation in the CAPN10 gene influences blood glucose levels in nondiabetic British subjects and that this is due, at least in part, to the effects of calpain-10 on the early insulin secretory response.

TL;DR: The age-related decrease in mtDNA copy number that was observed in human pancreatic islet preparations may contribute to the age-dependent decline in pancreatic beta cell insulin secretory capacity.

TL;DR: Examination of the biosynthetic gene clusters revealed that enzymes installing secondary post-translational modifications are more widespread than initially thought and the precursor peptides encoded within these clusters are more diverse than previously appreciated, demonstrating that the lanthipeptide sequence-function space remains largely underexplored.