M
Mark Walker
Researcher at University of Ottawa
Publications - 690
Citations - 63950
Mark Walker is an academic researcher from University of Ottawa. The author has contributed to research in topics: Population & Pregnancy. The author has an hindex of 97, co-authored 622 publications receiving 58554 citations. Previous affiliations of Mark Walker include Newcastle University & Queen's University.
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Journal ArticleDOI
Mitochondrial diabetes: investigation and identification of a novel mutation.
Stephen Lynn,Theresa M. Wardell,Mark A. Johnson,Patrick F. Chinnery,Mark E. Daly,Mark Walker,D.M. Turnbull +6 more
Journal ArticleDOI
Impaired beta cell glucose sensitivity and whole-body insulin sensitivity as predictors of hyperglycaemia in non-diabetic subjects
TL;DR: Impaired pancreatic beta cell glucose sensing and whole-body insulin sensitivity predict progression to hyperglycaemia, override the importance of the clinical risk factors and highlight potential metabolic targets for prevention strategies.
Journal ArticleDOI
The variable number of tandem repeats upstream of the insulin gene is a susceptibility locus for latent autoimmune diabetes in adults.
Minal Desai,Eleftheria Zeggini,V A Horton,Katharine R. Owen,Andrew T. Hattersley,Jonathan C. Levy,Graham A. Hitman,Mark Walker,Rury R. Holman,Mark I. McCarthy,Anne Clark +10 more
TL;DR: It is established that variation within the insulin gene region does influence susceptibility to LADA, with the direction and magnitude of effect indistinguishable from that previously reported for type 1 diabetes.
Journal ArticleDOI
A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk
Alisa K. Manning,Alisa K. Manning,Heather M. Highland,Heather M. Highland,Jessica A. Gasser,Xueling Sim,Taru Tukiainen,Taru Tukiainen,Pierre Fontanillas,Niels Grarup,Manuel A. Rivas,Anubha Mahajan,Adam E. Locke,Pablo Cingolani,Tune H. Pers,Ana Viñuela,Ana Viñuela,Andrew A. Brown,Andrew A. Brown,Ying Wu,Jason Flannick,Jason Flannick,Christian Fuchsberger,Eric R. Gamazon,Kyle J. Gaulton,Kyle J. Gaulton,Hae Kyung Im,Tanya M. Teslovich,Thomas W. Blackwell,Jette Bork-Jensen,Noël P. Burtt,Yuhui Chen,Todd Green,Christopher Hartl,Hyun Min Kang,Ashok Kumar,Ashok Kumar,Claes Ladenvall,Clement Ma,Loukas Moutsianas,Richard D. Pearson,John R. B. Perry,John R. B. Perry,John R. B. Perry,N. William Rayner,N. William Rayner,N. William Rayner,Neil R. Robertson,Neil R. Robertson,Laura J. Scott,Martijn van de Bunt,Martijn van de Bunt,Johan G. Eriksson,Antti Jula,Seppo Koskinen,Terho Lehtimäki,Aarno Palotie,Aarno Palotie,Aarno Palotie,Olli T. Raitakari,Olli T. Raitakari,Suzanne B.R. Jacobs,Jennifer Wessel,Audrey Y. Chu,Robert A. Scott,Mark O. Goodarzi,Christine Blancher,Gemma Buck,David Buck,Peter S. Chines,Stacey Gabriel,Anette P. Gjesing,Christopher J. Groves,Mette Hollensted,Jeroen R. Huyghe,Anne U. Jackson,Goo Jun,Johanne Marie Justesen,Massimo Mangino,Jacquelyn Murphy,Matt J. Neville,Robert C. Onofrio,Kerrin S. Small,Heather M. Stringham,Joseph Trakalo,Eric Banks,Jason Carey,Mauricio O. Carneiro,Mark A. DePristo,Yossi Farjoun,Timothy Fennell,Jacqueline I. Goldstein,Jacqueline I. Goldstein,George B. Grant,Martin Hrabé de Angelis,Jared Maguire,Benjamin M. Neale,Benjamin M. Neale,Ryan Poplin,Shaun Purcell,Shaun Purcell,Shaun Purcell,Thomas Schwarzmayr,Khalid Shakir,Joshua D. Smith,Tim M. Strom,Thomas Wieland,Jaana Lindström,Ivan Brandslund,Cramer Christensen,Gabriela L. Surdulescu,Timo A. Lakka,Alex S. F. Doney,Peter M. Nilsson,Nicholas J. Wareham,Claudia Langenberg,Tibor V. Varga,Paul W. Franks,Paul W. Franks,Paul W. Franks,Olov Rolandsson,Anders Rosengren,Vidya S. Farook,Farook Thameem,Sobha Puppala,Satish Kumar,Donna M. Lehman,Christopher P. Jenkinson,Joanne E. Curran,Daniel E. Hale,Sharon P. Fowler,Rector Arya,Ralph A. DeFronzo,Hanna E. Abboud,Ann-Christine Syvänen,Pamela J. Hicks,Nicholette D. Palmer,Maggie C.Y. Ng,Donald W. Bowden,Barry I. Freedman,Tõnu Esko,Reedik Mägi,Lili Milani,Evelin Mihailov,Andres Metspalu,Narisu Narisu,Leena Kinnunen,Lori L. Bonnycastle,Amy J. Swift,Dorota Pasko,Andrew R. Wood,João Fadista,Toni I. Pollin,Nir Barzilai,Gil Atzmon,Benjamin Glaser,Barbara Thorand,Konstantin Strauch,Annette Peters,Michael Roden,Martina Müller-Nurasyid,Liming Liang,Jennifer Kriebel,Thomas Illig,Harald Grallert,Christian Gieger,Christa Meisinger,Lars Lannfelt,Solomon K. Musani,Michael Griswold,Herman A. Taylor,Gregory A Wilson,Adolfo Correa,Heikki Oksa,William R. Scott,Uzma Afzal,Sian-Tsung Tan,Marie Loh,Marie Loh,Marie Loh,John C. Chambers,John C. Chambers,John C. Chambers,Jobanpreet Sehmi,Jaspal S. Kooner,Benjamin Lehne,Yoon Shin Cho,Jong-Young Lee,Bok-Ghee Han,Annemari Käräjämäki,Qibin Qi,Qibin Qi,Lu Qi,Lu Qi,Jinyan Huang,Frank B. Hu,Olle Melander,Marju Orho-Melander,Jennifer E. Below,David Aguilar,Tien Yin Wong,Jianjun Liu,Jianjun Liu,Chiea Chuen Khor,Kee Seng Chia,Wei-Yen Lim,Ching-Yu Cheng,Edmund Chan,E. Shyong Tai,Tin Aung,Allan Linneberg,Allan Linneberg,Bo Isomaa,Thomas Meitinger,Tiinamaija Tuomi,Liisa Hakaste,Jasmina Kravic,Marit E. Jørgensen,Torsten Lauritzen,Panos Deloukas,Kathleen Stirrups,Kathleen Stirrups,Katharine R. Owen,Andrew Farmer,Timothy M. Frayling,Stephen O'Rahilly,Mark Walker,Jonathan C. Levy,Dylan Hodgkiss,Andrew T. Hattersley,Teemu Kuulasmaa,Alena Stančáková,Inês Barroso,Inês Barroso,Dwaipayan Bharadwaj,Juliana C.N. Chan,Giriraj R. Chandak,Mark J. Daly,Peter Donnelly,Peter Donnelly,Shah Ebrahim,Paul Elliott,Tasha E. Fingerlin,Philippe Froguel,Cheng Hu,Weiping Jia,Ronald C.W. Ma,Gilean McVean,Taesung Park,Dorairaj Prabhakaran,Manjinder S. Sandhu,Manjinder S. Sandhu,James Scott,Robert Sladek,Nikhil Tandon,Yik Ying Teo,Eleftheria Zeggini,Richard M. Watanabe,Heikki A. Koistinen,Heikki A. Koistinen,Heikki A. Koistinen,Y. Antero Kesäniemi,Matti Uusitupa,Tim D. Spector,Veikko Salomaa,Rainer Rauramaa,Colin N. A. Palmer,Inga Prokopenko,Inga Prokopenko,Inga Prokopenko,Andrew D. Morris,Richard N. Bergman,Francis S. Collins,Lars Lind,Erik Ingelsson,Jaakko Tuomilehto,Fredrik Karpe,Leif Groop,Torben Jørgensen,Torben Jørgensen,Torben Hansen,Torben Hansen,Oluf Pedersen,Johanna Kuusisto,Gonçalo R. Abecasis,Graeme I. Bell,John Blangero,Nancy J. Cox,Ravindranath Duggirala,Mark Seielstad,Mark Seielstad,James G. Wilson,Josée Dupuis,Samuli Ripatti,Samuli Ripatti,Craig L. Hanis,Jose C. Florez,Karen L. Mohlke,James B. Meigs,James B. Meigs,Markku Laakso,Andrew P. Morris,Andrew P. Morris,Andrew P. Morris,Michael Boehnke,David Altshuler,Mark I. McCarthy,Mark I. McCarthy,Anna L. Gloyn,Anna L. Gloyn,Cecilia M. Lindgren,Cecilia M. Lindgren,Cecilia M. Lindgren +312 more
TL;DR: The allelic spectrum for coding variants in AKT2 associated with disorders of glucose homeostasis is extended and bidirectional effects of variants within the pleckstrin homology domain ofAKT2 are demonstrated.
Journal ArticleDOI
Comparison of maternal risk factors between placental abruption and placenta previa.
TL;DR: The effects of maternal age, race, parity, and previous cesarean section were stronger on placenta previa than on placental abruption, and the effects of cigarette smoking, alcohol drinking, and prenatal care were stronger.