M
Mark Walker
Researcher at University of Ottawa
Publications - 690
Citations - 63950
Mark Walker is an academic researcher from University of Ottawa. The author has contributed to research in topics: Population & Pregnancy. The author has an hindex of 97, co-authored 622 publications receiving 58554 citations. Previous affiliations of Mark Walker include Newcastle University & Queen's University.
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Journal ArticleDOI
External validation of ELASTIC NET regression models including newborn metabolomic markers for postnatal gestational age estimation in East and South-East Asian infants
Steven Hawken,Steven Hawken,Malia S.Q. Murphy,Robin Ducharme,A. Brianne Bota,Lindsay A. Wilson,Wei Cheng,Ma-Am Joy R. Tumulak,Maria Melanie Liberty Alcausin,Ma. Elouisa L. Reyes,Wenjuan Qiu,Beth K. Potter,Julian Little,Mark Walker,Lin Zhang,Lin Zhang,Carmencita Padilla,Carmencita Padilla,Pranesh Chakraborty,Pranesh Chakraborty,Kumanan Wilson +20 more
TL;DR: Accuracy of metabolic GA algorithms was attenuated when applied in external settings, and models including metabolomic markers demonstrated higher accuracy than models using sex and birth weight alone.
Journal ArticleDOI
Reply of the Authors: Risk of birth defects increased in pregnancies conceived by assisted human reproduction
Posted ContentDOI
Genome-wide analysis of Structural Variants in Parkinson’s Disease using Short-Read Sequencing data
Kimberley Billingsley,Jinhui Ding,Pilar Alvarez Jerez,Anastasia Illarionova,Francis P. Grenn,Mary B. Makarious,Anni Moore,Dan Vitale,Xylena Reed,Dena G. Hernandez,Ali Torkamani,Mina Ryten,John Hardy,Ruth Chia,Sonja W. Scholz,Bryan J. Traynor,Clifton L. Dalgard,Debra Ehrlich,Toshiko Tanaka,Luigi Ferrucci,Thomas G. Beach,Geidy E. Serrano,John P. Quinn,Vivien J. Bubb,Ryan L. Collins,Xuefang Zhao,Mark Walker,Emma Pierce-Hoffman,Harrison Brand,Michael E. Talkowski,Bradford Casey,Mark R. Cookson,Andrew Markham,Mike A. Nalls,Medhat Mahmoud,Fritz J. Sedlazeck,Cornelis Blauwendraat,J. Raphael Gibbs,Andrew B. Singleton +38 more
TL;DR: This study leveraged the GATK-SV pipeline to detect and genotype structural variants in 7,772 short-read sequencing data and generated a subset of matched whole-genome Oxford Nanopore Technologies long- read sequencing data from the PPMI cohort to allow for comprehensive structural variant confirmation.
Journal ArticleDOI
Dietary metabolite profiling brings new insight into the relationship between nutrition and metabolic risk: An IMI DIRECT study
Rebeca Eriksen,Isabel Garcia Perez,Joram M. Posma,Mark Haid,Sapna Sharma,Cornelia Prehn,Louise Thomas,Robert W. Koivula,Robert W. Koivula,Roberto Bizzotto,Andrea Mari,Giuseppe N. Giordano,Imre Pavo,Jochen M. Schwenk,Federico De Masi,Konstantinos D. Tsirigos,Søren Brunak,Søren Brunak,Ana Viñuela,Anubha Mahajan,Timothy J. McDonald,Tarja Kokkola,Femke Rutter,Harriet Teare,Tue H. Hansen,Juan P. Fernandez,Angus G. Jones,Christopher Jennison,Mark Walker,Mark I. McCarthy,Oluf Pedersen,Hartmut Ruetten,Ian M Forgie,Jimmy D. Bell,Ewan R. Pearson,Paul W. Franks,Jerzy Adamski,Jerzy Adamski,Elaine Holmes,Gary Frost,Gary Frost +40 more
TL;DR: Plasma dietary metabolite profiling provides objective measures of diet intake, showing a relationship to glycaemic deterioration and cardiometabolic health in people at risk of or living with type 2 diabetes.
Journal Article
Genetic and Functional Analyses Identify NAT2 as a Human Insulin Sensitivity Gene
Joshua W. Knowles,Ke Hao,Weija Xie,Michael N. Weedon,Zhongyang Zhang,Jussil Paaanen,Mark O. Goodarzi,Ola Hansson,James S. Pankow,Indumathi Chenemsetty,Ivan Carcamo-Orive,Themisrocles Assimes,Andrew D. Morris,Yii-Der Ida Chen,Eric E. Schadt,Ville-Petteri Mäkinen,Xia Yang,Fahi Abbasi,Alan D. Attie,Mark P. Keller,Danielle M. Greenawalt,Jerome I. Rotter,Alan Sinako,Agnes Hsiung,Heather J. Cordell,Gerald M. Reaven,Leif Groop,Markku Laakso,Erik Ingelsson,Timothy M. Frayling,Mark Walker,Thomas Quertermous +31 more