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Marloes W J T Janssen-van den Broek
Researcher at Eindhoven University of Technology
Publications - 4
Citations - 327
Marloes W J T Janssen-van den Broek is an academic researcher from Eindhoven University of Technology. The author has contributed to research in topics: Pulmonary valve & Decellularization. The author has an hindex of 4, co-authored 4 publications receiving 249 citations.
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Journal ArticleDOI
In situ heart valve tissue engineering using a bioresorbable elastomeric implant - From material design to 12 months follow-up in sheep.
Jolanda Kluin,Hanna Talacua,Anthal I.P.M. Smits,Maximilian Y. Emmert,Marieke Brugmans,Emanuela S. Fioretta,Petra E. Dijkman,Serge H. M. Söntjens,Renee Duijvelshoff,Sylvia Dekker,Marloes W J T Janssen-van den Broek,Valentina Lintas,Aryan Vink,Simon P. Hoerstrup,Simon P. Hoerstrup,Henk M. Janssen,Patricia Y. W. Dankers,Frank P. T. Baaijens,Carlijn V. C. Bouten +18 more
TL;DR: A fibrous valvular scaffold is designed, fabricated from a novel supramolecular elastomer, that enables endogenous cells to enter and produce matrix and offer new perspectives for endogenous heart valve replacement starting from a readily-available synthetic graft that is compatible with surgical and transcatheter implantation procedures.
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Age-Dependent Changes in Geometry, Tissue Composition and Mechanical Properties of Fetal to Adult Cryopreserved Human Heart Valves.
Daphne van Geemen,Alf Ana Soares,Pim J A Oomen,Anita Anita Driessen-Mol,Marloes W J T Janssen-van den Broek,Antoon J. van den Bogaerdt,Ad J.J.C. Bogers,Marie-José Goumans,Frank P. T. Baaijens,Carlijn V. C. Bouten +9 more
TL;DR: An extended data set of structure-function properties of cryopreserved human pulmonary and aortic heart valves is presented, providing age-specific information for living valve replacements and can be used to evaluate and optimize future therapies, such as tissue engineering of heart valves.
Journal ArticleDOI
Synergy between Rho signaling and matrix density in cyclic stretch-induced stress fiber organization.
TL;DR: Results from this study highlight a synergistic action between matrix remodeling and Rho signaling in cyclic-stretch-induced stress fiber organization in 3-D tissue.
Journal ArticleDOI
A Bioreactor to Identify the Driving Mechanical Stimuli of Tissue Growth and Remodeling.
Mathieu A.J. van Kelle,Pim J A Oomen,Jurgen A Bulsink,Marloes W J T Janssen-van den Broek,Richard G.P. Lopata,Marcel C. M. Rutten,S Sandra Loerakker,Carlijn V. C. Bouten +7 more
TL;DR: A novel "versatile tissue growth and remodeling" (Vertigro) bioreactor was developed that is capable of tissue culture and mechanical stimulation for a prolonged time period, while simultaneously performing mechanical testing.