M
Maximilian Y. Emmert
Researcher at University of Zurich
Publications - 241
Citations - 5610
Maximilian Y. Emmert is an academic researcher from University of Zurich. The author has contributed to research in topics: Heart valve & Medicine. The author has an hindex of 38, co-authored 209 publications receiving 4525 citations. Previous affiliations of Maximilian Y. Emmert include Triemli Hospital & Technical University of Berlin.
Papers
More filters
Journal ArticleDOI
In situ heart valve tissue engineering using a bioresorbable elastomeric implant - From material design to 12 months follow-up in sheep.
Jolanda Kluin,Hanna Talacua,Anthal I.P.M. Smits,Maximilian Y. Emmert,Marieke Brugmans,Emanuela S. Fioretta,Petra E. Dijkman,Serge H. M. Söntjens,Renee Duijvelshoff,Sylvia Dekker,Marloes W J T Janssen-van den Broek,Valentina Lintas,Aryan Vink,Simon P. Hoerstrup,Simon P. Hoerstrup,Henk M. Janssen,Patricia Y. W. Dankers,Frank P. T. Baaijens,Carlijn V. C. Bouten +18 more
TL;DR: A fibrous valvular scaffold is designed, fabricated from a novel supramolecular elastomer, that enables endogenous cells to enter and produce matrix and offer new perspectives for endogenous heart valve replacement starting from a readily-available synthetic graft that is compatible with surgical and transcatheter implantation procedures.
Journal ArticleDOI
Minimally-invasive implantation of living tissue engineered heart valves: a comprehensive approach from autologous vascular cells to stem cells.
Dörthe Schmidt,Petra E. Dijkman,Anita Anita Driessen-Mol,Rene Stenger,Christine Mariani,Arja Puolakka,Marja Rissanen,Thorsten Deichmann,Bernhard Odermatt,Benedikt Weber,Maximilian Y. Emmert,Gregor Zünd,Frank P. T. Baaijens,Simon P. Hoerstrup +13 more
TL;DR: In this paper, a tissue engineered heart valve (TEHV) was implanted as pulmonary valve replacement in sheep and evaluated by echocardiography and angiography up to 8 weeks.
Journal ArticleDOI
Off-the-shelf human decellularized tissue-engineered heart valves in a non-human primate model
Benedikt Weber,Petra E. Dijkman,Jacques Scherman,Bart Sanders,Maximilian Y. Emmert,Jürg Grünenfelder,Renier Verbeek,Mona Bracher,Melanie Black,Thomas Franz,Jeroen Kortsmit,Peter Modregger,Peter Modregger,Silvia Peter,Silvia Peter,Marco Stampanoni,Marco Stampanoni,Jerome Robert,Debora Kehl,Marina van Doeselaar,Martin Schweiger,Chad Brokopp,Thomas Wälchli,Thomas Wälchli,Volkmar Falk,Peter Zilla,Anita Anita Driessen-Mol,Frank P. T. Baaijens,Simon P. Hoerstrup +28 more
TL;DR: The results suggest that human cell-derived bioengineered decellularized materials represent a promising and clinically relevant starter matrix for heart valve tissue engineering and may ultimately overcome the limitations of currently used valve replacements by providing homologous, non-immunogenic, off-the-shelf replacement constructs.
Journal ArticleDOI
Transcatheter implantation of homologous "off-the-shelf" tissue-engineered heart valves with self-repair capacity: long-term functionality and rapid in vivo remodeling in sheep.
Anita Anita Driessen-Mol,Maximilian Y. Emmert,Petra E. Dijkman,Laura Frese,Bart Sanders,Benedikt Weber,Nikola Cesarovic,Michèle Sidler,Jori Leenders,Rolf Jenni,Jürg Grünenfelder,Volkmar Falk,Frank P. T. Baaijens,Simon P. Hoerstrup +13 more
TL;DR: The feasibility and long-term functionality of transcatheter-based homologous off-the-shelf tissue engineered heart valves are demonstrated in a relevant pre-clinical model and substantially simplify previous tissue engineering concepts toward clinical translation.
Journal ArticleDOI
Hyperfibrinolysis diagnosed by rotational thromboelastometry (ROTEM) is associated with higher mortality in patients with severe trauma.
Oliver M. Theusinger,Guido A. Wanner,Maximilian Y. Emmert,Adrian T. Billeter,Jennifer Eismon,Burkhardt Seifert,Hans-Peter Simmen,Donat R. Spahn,Werner Baulig +8 more
TL;DR: Mortality from hyperfibrinolysis is significantly higher in trauma compared with nontrauma patients, and hyperfinema is an independent factor predicting mortality in trauma patients.