M
Martha H. Mulks
Researcher at Michigan State University
Publications - 63
Citations - 2785
Martha H. Mulks is an academic researcher from Michigan State University. The author has contributed to research in topics: Actinobacillus pleuropneumoniae & Proteases. The author has an hindex of 27, co-authored 63 publications receiving 2589 citations. Previous affiliations of Martha H. Mulks include University of Washington & Centers for Disease Control and Prevention.
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Journal ArticleDOI
Pre-B-cell colony-enhancing factor, whose expression is up-regulated in activated lymphocytes, is a nicotinamide phosphoribosyltransferase, a cytosolic enzyme involved in NAD biosynthesis.
Anthony Rongvaux,Robin J. Shea,Martha H. Mulks,Daniel Gigot,Jacques Urbain,Oberdan Leo,Fabienne Andris +6 more
TL;DR: It is demonstrated that the murine homologue of the previously identified human "pre‐B‐cell colony‐enhancing factor" (PBEF) gene coding for a putative cytokine has been identified by screening a subtractive library enriched in genes expressed in activated T lymphocytes, and NAD biosynthesis may play an important role in lymphocyte activation.
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The Neisseria type 2 IgA1 protease cleaves LAMP1 and promotes survival of bacteria within epithelial cells
Lan Lin,Patricia Ayala,Jason A. Larson,Martha H. Mulks,Minoru Fukuda,Sven R. Carlsson,Caroline A. Enns,Magdalene So +7 more
TL;DR: IgA1 protease cleavage of LAMP1 promotes intracellular survival of pathogenic Neisseria spp.
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Identification of a plasmid-encoded gene from Haemophilus ducreyi which confers NAD independence.
TL;DR: This study demonstrates that this phenotype can be determined by a single gene, nadV, whose presence allows NAD-independent growth of Haemophilus influenzae and Actinobacillus pleuropneumoniae and identifies a function for this gene in the Pasteurellaceae to help to elucidate the role of its homologues in other species.
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Poly -N -acetylglucosamine mediates biofilm formation and antibiotic resistance in Actinobacillus pleuropneumoniae
Era A. Izano,Irina Sadovskaya,Evgeny Vinogradov,Martha H. Mulks,Kabilan Velliyagounder,Chandran Ragunath,William B. Kher,Narayanan Ramasubbu,Saïd Jabbouri,Malcolm B. Perry,Jeffrey B. Kaplan +10 more
TL;DR: Findings suggest that PGA functions as a major biofilm adhesin in A. pleuropneumoniae, and may have relevance to the colonization and pathogenesis of A. Pleurop pneumoniae in pigs.
Journal ArticleDOI
IgA protease production as a characteristic distinguishing pathogenic from harmless neisseriaceae
Martha H. Mulks,Andrew G. Plaut +1 more
TL;DR: The finding that IgA protease activity is linked specifically to the pathogenic neisseria suggests that the enzyme may be involved in the pathogenesis of neisserial infection.