Martin Heisig

TL;DR: It is suggested that InlC promotes bacterial dissemination by relieving cortical tension, thereby enhancing the ability of motile bacteria to deform the plasma membrane into protrusions.

TL;DR: The findings suggest that the direct viral oncolysis of tumor cells and the virus-dependent activation of tumor-associated host immune cells could be crucial parts of anti-tumor mechanism in STSA-1 xenografts.

TL;DR: Quantitative analysis of bacterial tumor targeting demonstrated that attenuated, invasive Shigella flexneri primarily infected TAMs after systemic administration, supporting TAMs as useful targets for antitumor therapy and highlighting attenuated bacterial pathogens as potential tools.

TL;DR: Data show that an antifreeze protein facilitates host control of bacterial infections and suggest therapeutic strategies for countering pathogens.

TL;DR: It is demonstrated that the GLV-1h68 virus has a great potential for treatment of human prostate carcinoma and led to strong inflammatory and oncolytic effects resulting in drastic reduction of regional lymph nodes with PC-3 metastases.