Masao Ono

TL;DR: An anatomical difference in the distribution in the human airway of the different binding molecules preferred by the avian and human influenza viruses is demonstrated to provide a rational explanation for why H5N1 viruses at present rarely infect and spread between humans although they can replicate efficiently in the lungs.

TL;DR: Results indicate that RNF213 is the first identified susceptibility gene for MMD, and it is confirmed that mature lymphocytes express higher levels of Rnf213 mRNA than their immature counterparts.

TL;DR: The data suggest that Wnt/LRP5 signaling contributes to the glucose-induced insulin secretion in the islets, which is also required for normal cholesterol and glucose metabolism.

TL;DR: A novel model for Goodpasture's syndrome is reported using mice deficient in a central regulatory receptor for immunoglobulin (Ig)G antibody expression and function, the type IIB Fc receptor for IgG (FcgammaRIIB) and it is suggested that it may play a role in the pathogenesis of human GPS.

TL;DR: Analysis of plasma lipoproteins in mice lacking LRP5, apolipoprotein E (apoE), or both and histological examination revealed highly advanced arthrosclerosis, suggest that L RP5 mediates both apoE-dependent and apo E-independent catabolism of plasma lipid metabolism.