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Massimo Tommasino

Researcher at International Agency for Research on Cancer

Publications -  334
Citations -  14170

Massimo Tommasino is an academic researcher from International Agency for Research on Cancer. The author has contributed to research in topics: Cancer & HPV infection. The author has an hindex of 62, co-authored 312 publications receiving 12239 citations. Previous affiliations of Massimo Tommasino include German Cancer Research Center & World Health Organization.

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The E6E7 oncoproteins of cutaneous human papillomavirus type 38 interfere with the interferon pathway.

TL;DR: It is shown that HPV-38 E6 and E7 affect the IFN-induced up-regulation of MHC class I and encodes oncoproteins that potentially contribute to the evasion of host immune surveillance.
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Human papillomavirus E7 proteins stimulate proliferation independently of their ability to associate with retinoblastoma protein.

TL;DR: A comparative analysis of the different E7 proteins demonstrates that the oncogenicity of a HPV type is not determined by the ability of E7 to associate with the pocket proteins, and provides evidence that different E 7s alter the regulation of the cell cycle by diverse mechanism(s).
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Case-control study of cutaneous human papillomavirus infection in Basal cell carcinoma of the skin.

TL;DR: The combined serology and tumor DNA results suggest that β HPV types may have a role in BCC, with type-specific associations observed for HPV8 and HPV23, whereas no association was observed between β-HPV seropositivity and β- HPV DNA-negative BCC.