M
Massimo Tommasino
Researcher at International Agency for Research on Cancer
Publications - 334
Citations - 14170
Massimo Tommasino is an academic researcher from International Agency for Research on Cancer. The author has contributed to research in topics: Cancer & HPV infection. The author has an hindex of 62, co-authored 312 publications receiving 12239 citations. Previous affiliations of Massimo Tommasino include German Cancer Research Center & World Health Organization.
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Journal ArticleDOI
Human papillomavirus E6 and E7 oncoproteins affect the expression of cancer-related microRNAs: additional evidence in HPV-induced tumorigenesis.
Maria Vincenza Chiantore,Giorgio Mangino,Marco Iuliano,Maria Simona Zangrillo,Ilaria De Lillis,Gabriele Vaccari,Rosita Accardi,Massimo Tommasino,Sandra Columba Cabezas,Maurizio Federico,Gianna Fiorucci,Giovanna Romeo,Giovanna Romeo +12 more
TL;DR: HPV E6 and/or E7 oncoprotein expression can induce the deregulation of some miRNAs, and MiR-222, a key miRNA deregulated in many cancers, was identified in exosomes from K16 cells.
Journal Article
New functions of an old protein: the eukaryotic porin or voltage dependent anion selective channel (VDAC)
Vito De Pinto,Angela Messina,Rosita Accardi,Rita Aiello,Francesca Guarino,Marianna Flora Tomasello,Massimo Tommasino,Gianluca Tasco,Rita Casadio,Roland Benz,Francesca De Giorgi,François Ichas,Mark Baker,Alfons Lawen +13 more
TL;DR: It is affirm that nowadays the eukaryotic porin (or VDAC) is studied in a more general cellular contest, looking at the interactions and integration with other molecules, since VD AC is in a crucial position in the cell, forming the main interface between the mitochondrial and the cellular metabolisms.
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Case–control study of genus‐beta human papillomaviruses in plucked eyebrow hairs and cutaneous squamous cell carcinoma
Michelle R. Iannacone,Tarik Gheit,Herbert Pfister,Anna R. Giuliano,Jane L. Messina,Neil A. Fenske,Basil S. Cherpelis,Vernon K. Sondak,Richard G. Roetzheim,Steffi Silling,Michael Pawlita,Massimo Tommasino,Dana E. Rollison +12 more
TL;DR: SCC cases were more likely than controls to have HPV DNA+ EBH for single and multiple HPV types, providing additional support for the potential role of genus‐beta HPV infections in SCC development.
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Separation of C/EBPα-mediated proliferation arrest and differentiation pathways
Christine Müller,Marianna Alunni-Fabbroni,Elisabeth Kowenz-Leutz,Xianming Mo,Massimo Tommasino,Achim Leutz +5 more
TL;DR: C/EBPalpha-mediated proliferation arrest and differentiation pathways can be separated by the E7 oncoprotein of the "high-risk" human papilloma virus without compromising the transactivation activity of C/ EBPalpha or its ability to participate in differentiation.
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Case-control study of Merkel cell polyomavirus infection and cutaneous squamous cell carcinoma.
Dana E. Rollison,Anna R. Giuliano,Jane L. Messina,Neil A. Fenske,Basil S. Cherpelis,Vernon K. Sondak,Richard G. Roetzheim,Michelle R. Iannacone,Kristina M. Michael,Tarik Gheit,Tim Waterboer,Massimo Tommasino,Michael Pawlita +12 more
TL;DR: Past exposure to MCV may be a risk factor for squamous cell carcinomas and understanding the role of viral infections in the development of nonmelanoma skin cancer could lead to novel prevention strategies.