M
Massimo Tommasino
Researcher at International Agency for Research on Cancer
Publications - 334
Citations - 14170
Massimo Tommasino is an academic researcher from International Agency for Research on Cancer. The author has contributed to research in topics: Cancer & HPV infection. The author has an hindex of 62, co-authored 312 publications receiving 12239 citations. Previous affiliations of Massimo Tommasino include German Cancer Research Center & World Health Organization.
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Journal ArticleDOI
The role of TP53 in Cervical carcinogenesis
Massimo Tommasino,Rosita Accardi,Sandra Caldeira,Wen Dong,Ilaria Malanchi,Anouk Smet,Ingeborg Zehbe +6 more
TL;DR: The ability to promote p53 degradation is an exclusive property of E6 from the high‐risk HPV types, and the low‐risk E6 proteins lack this activity, although they can bind p53.
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The E6 and E7 Proteins of the Cutaneous Human Papillomavirus Type 38 Display Transforming Properties
Sandra Caldeira,Ingeborg Zehbe,Rosita Accardi,Ilaria Malanchi,Wen Dong,Marianna Giarrè,Marianna Giarrè,Ethel Michele De Villiers,Raffaele Filotico,Petra Boukamp,Massimo Tommasino,Massimo Tommasino +11 more
TL;DR: This study characterized the in vitro properties of E7 proteins of three cutaneous HPV types, 10, 20, and 38, and shows that HPV38 E7 is able to inactivate the tumor suppressor pRb and induces loss of G1/S transition control, a key event in carcinogenesis.
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Smoking as a major risk factor for cervical cancer and pre‐cancer: Results from the EPIC cohort
Esther Roura,Xavier Castellsagué,Michael Pawlita,Noémie Travier,Tim Waterboer,N. Margall,F. Xavier Bosch,Silvia de Sanjosé,Joakim Dillner,Inger T. Gram,Anne Tjønneland,Christian Munk,Valeria Pala,Domenico Palli,Kay-Tee Khaw,Ruanne V. Barnabas,Ruanne V. Barnabas,Kim Overvad,Françoise Clavel-Chapelon,Marie-Christine Boutron-Ruault,Guy Fagherazzi,Rudolf Kaaks,Annekatrin Lukanova,Annika Steffen,Antonia Trichopoulou,Dimitrios Trichopoulos,Dimitrios Trichopoulos,Eleni Klinaki,Rosario Tumino,Carlotta Sacerdote,Salvatore Panico,Hendrik B. Bueno-de-Mesquita,Hendrik B. Bueno-de-Mesquita,Petra H.M. Peeters,Petra H.M. Peeters,Eiliv Lund,Elisabete Weiderpass,M. Luisa Redondo,María José Sánchez,María José Tormo,Aurelio Barricarte,Nerea Larrañaga,Johanna Ekström,Maria Hortlund,David Lindquist,Nicholas J. Wareham,Ruth C. Travis,Sabina Rinaldi,Massimo Tommasino,Silvia Franceschi,Elio Riboli +50 more
TL;DR: A total of 308,036 women were selected from the European Prospective Investigation into Cancer and Nutrition (EPIC) to evaluate the association between tobacco smoking and the risk of cervical intr...
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Low human papillomavirus prevalence in head and neck cancer: results from two large case–control studies in high-incidence regions
Karina Braga Ribeiro,José Eduardo Levi,Michael Pawlita,Sergio Koifman,Elena Matos,José Eluf-Neto,Victor Wünsch-Filho,Maria Paula Curado,Oxana Shangina,David Zaridze,Neonila Szeszenia-Dabrowska,Jolanta Lissowska,Alexander W. Daudt,Ana M. B. Menezes,Vladimir Bencko,Dana Mates,Leticia Fernandez,Eleonora Fabianova,Tarik Gheit,Massimo Tommasino,Paolo Boffetta,Paul Brennan,Tim Waterboer +22 more
TL;DR: The proportion of head and neck cancer caused by HPV may vary substantially between different geographical regions and studies that are designed to evaluate the impact of HPV vaccination on HNSCC need to consider this heterogeneity.
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Synthesis and assembly of virus-like particles of human papillomaviruses type 6and Type 16 in fission yeast Schizosaccharomyces pombe
Toshiyuki Sasagawa,Peter Pushko,Graham Steers,Steve E. Gschmeissner,M.A. Nasser Hajibagheri,John T. Finch,Lionel Crawford,Massimo Tommasino +7 more
TL;DR: The results suggest that the L2 is not incorporated into the VLP synthesized in yeast, and the capsid proteins were localized in the nucleus by indirect immunofluorescence and cell fractionation analyses.