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Matthias Meyer

Researcher at Max Planck Society

Publications -  182
Citations -  37857

Matthias Meyer is an academic researcher from Max Planck Society. The author has contributed to research in topics: Ancient DNA & Population. The author has an hindex of 72, co-authored 170 publications receiving 31843 citations. Previous affiliations of Matthias Meyer include Lund University & MacDiarmid Institute for Advanced Materials and Nanotechnology.

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Manual and automated preparation of single-stranded DNA libraries for the sequencing of DNA from ancient biological remains and other sources of highly degraded DNA

TL;DR: An updated protocol for single-stranded sequencing library preparation suitable for highly degraded DNA from ancient remains or other sources is presented, which can be performed manually or in an automated fashion.
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Extending the spectrum of DNA sequences retrieved from ancient bones and teeth.

TL;DR: It is shown that much shorter DNA fragments are present in ancient skeletal remains but lost during DNA extraction, and the combination of DNA extraction and library preparation techniques described here substantially increases the yield of DNA sequences from ancient remains and provides access to a yet unexploited source of highly degraded DNA fragments.
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Long-Term Balancing Selection in LAD1 Maintains a Missense Trans-Species Polymorphism in Humans, Chimpanzees, and Bonobos

TL;DR: This work sequenced the exome of 20 humans, 20 chimpanzees, and 20 bonobos and detected eight coding trans-species polymorphisms (trSNPs) that are shared among the three species and have segregated for approximately 14 My of independent evolution; the majority of these trSNPs were found in three genes of the major histocompatibility locus cluster, but one coding trSNP was uncovered in the gene LAD1.