M
Mauricio Rocha-Martins
Researcher at Max Planck Society
Publications - 17
Citations - 1275
Mauricio Rocha-Martins is an academic researcher from Max Planck Society. The author has contributed to research in topics: Progenitor cell & Retina. The author has an hindex of 7, co-authored 16 publications receiving 724 citations. Previous affiliations of Mauricio Rocha-Martins include Instituto Gulbenkian de Ciência & Federal University of Rio de Janeiro.
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Journal ArticleDOI
Content-aware image restoration: pushing the limits of fluorescence microscopy.
Martin Weigert,Uwe Schmidt,Tobias Boothe,Andreas Müller,Alexandr Dibrov,Akanksha Jain,Benjamin Wilhelm,Deborah Schmidt,Coleman Broaddus,Siân Culley,Siân Culley,Mauricio Rocha-Martins,Fabián Segovia-Miranda,Caren Norden,Ricardo Henriques,Ricardo Henriques,Marino Zerial,Michele Solimena,Jochen C. Rink,Pavel Tomancak,Loic Royer,Florian Jug,Eugene W. Myers,Eugene W. Myers +23 more
TL;DR: This work shows how content-aware image restoration based on deep learning extends the range of biological phenomena observable by microscopy by bypassing the trade-offs between imaging speed, resolution, and maximal light exposure that limit fluorescence imaging to enable discovery.
Posted ContentDOI
Content-Aware Image Restoration: Pushing the Limits of Fluorescence Microscopy
Martin Weigert,Uwe Schmidt,Tobias Boothe,Andreas Müller,Alexandr Dibrov,Akanksha Jain,Benjamin Wilhelm,Deborah Schmidt,Coleman Broaddus,Siân Culley,Mauricio Rocha-Martins,Fabián Segovia-Miranda,Caren Norden,Ricardo Henriques,Marino Zerial,Michele Solimena,Jochen C. Rink,Pavel Tomancak,Loic Royer,Florian Jug,Eugene W. Myers,Eugene W. Myers +21 more
TL;DR: This work shows how deep learning enables biological observations beyond the physical limitations of microscopes, and illustrates how microscopy images can be restored even if 60-fold fewer photons are used during acquisition.
Journal ArticleDOI
Neuronal Migration and Lamination in the Vertebrate Retina
TL;DR: This work discusses neuronal migration and lamination in the vertebrate retina and summarizes the knowledge on these aspects of retinal development, as well as stating the open questions and future directions in this exciting field.
Journal ArticleDOI
Avoiding Pitfalls of Internal Controls: Validation of Reference Genes for Analysis by qRT-PCR and Western Blot throughout Rat Retinal Development
TL;DR: Putative housekeeping genes exhibit significant variation in both mRNA and protein content during retinal development, and it is shown that distinct combinations of internal controls fit for each experimental set in the case of qRT-PCR and that MAPK1 is a reliable loading control for Western blot.
Journal ArticleDOI
Independent modes of ganglion cell translocation ensure correct lamination of the zebrafish retina
TL;DR: It is shown that retinal ganglion cells can move by two different modes across the embryonic zebrafish retina and that correct RGC translocation is crucial for neuronal lamination and retinal development.