M
Mauro Pala
Researcher at National Cancer Research Institute
Publications - 44
Citations - 2036
Mauro Pala is an academic researcher from National Cancer Research Institute. The author has contributed to research in topics: DNA damage & DNA fragmentation. The author has an hindex of 17, co-authored 43 publications receiving 1822 citations. Previous affiliations of Mauro Pala include University of Genoa & Polaris Industries.
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Journal ArticleDOI
Coexpression of CD49b and LAG-3 identifies human and mouse T regulatory type 1 cells
Nicola Gagliani,Chiara F. Magnani,Samuel Huber,Monica E. Gianolini,Monica E. Gianolini,Mauro Pala,Paula Licona-Limón,Binggege Guo,De'Broski R. Herbert,Alessandro Bulfone,Filippo Trentini,Clelia Di Serio,Rosa Bacchetta,Marco Andreani,Leonie Brockmann,Silvia Gregori,Richard A. Flavell,Maria Grazia Roncarolo +17 more
TL;DR: The coexpression of CD49b and LAG-3 enables the isolation of highly suppressive human Tr 1 cells from in vitro anergized cultures and allows the tracking of Tr1 cells in the peripheral blood of subjects who developed tolerance after allogeneic hematopoietic stem cell transplantation.
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Sustained Activation of mTOR Pathway in Embryonic Neural Stem Cells Leads to Development of Tuberous Sclerosis Complex-Associated Lesions
Laura Magri,Marco Cambiaghi,Manuela Cominelli,Clara Alfaro-Cervello,Marco Cursi,Mauro Pala,Alessandro Bulfone,José Manuel García-Verdugo,Letizia Leocani,Fabio Minicucci,Pietro Luigi Poliani,Rossella Galli +11 more
TL;DR: Removing Tsc1 in Emx1-expressing embryonic telencephalic neural stem cells (NSCs) and finding that mutant mice faithfully recapitulated TSC neuropathological lesions found that finely tuned mTOR activation in embryonic NSCs may be critical to prevent development of TSC-associated brain lesions.
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Epidermal Growth Factor Receptor Expression Identifies Functionally and Molecularly Distinct Tumor-Initiating Cells in Human Glioblastoma Multiforme and Is Required for Gliomagenesis
Stefania Mazzoleni,Letterio S. Politi,Mauro Pala,Manuela Cominelli,Alberto Franzin,Lucia Sergi Sergi,Andrea Falini,Michele De Palma,Alessandro Bulfone,Pietro Luigi Poliani,Rossella Galli +10 more
TL;DR: It is shown that multiple GBM cell subpopulations could be purified from the specimens of patients with GBM and from cancer stem cell (CSC) lines based on the expression of EGFR and of other putative CSC markers, suggesting that EGFR plays a fundamental role in gliomagenesis.
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Monitoring Low Benzene Exposure: Comparative Evaluation of Urinary Biomarkers, Influence of Cigarette Smoking, and Genetic Polymorphisms
Silvia Fustinoni,Dario Consonni,Laura Campo,Marina Buratti,Antonio Colombi,Angela Cecilia Pesatori,Matteo Bonzini,Pier Alberto Bertazzi,Vito Foà,Seymour Garte,Peter B. Farmer,Leonard S. Levy,Mauro Pala,Federico Valerio,Vincenzo Fontana,Arianna Desideri,Domenico Franco Merlo +16 more
TL;DR: In the range of investigated benzene levels, smoking may be regarded as the major source of benzene intake; among the study indices, U-benzene is the marker of choice for biomonitoring low-level occupational and environmental benzene exposure.
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Pinus nigra and Pinus pinaster needles as passive samplers of polycyclic aromatic hydrocarbons.
Maria Teresa Piccardo,Mauro Pala,Bruna Bonaccurso,Anna Stella,Anna Redaelli,Gaudenzio Paola,Federico Valerio +6 more
TL;DR: Nine polycyclic aromatic hydrocarbons were analysed in pine needles of different ages collected from two species, Pinus nigra and Pinus pinaster, in seven sites located along a transect from a suburban to a rural area of Genoa (Italy).