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Michael Brecht

Researcher at Humboldt University of Berlin

Publications -  109
Citations -  5612

Michael Brecht is an academic researcher from Humboldt University of Berlin. The author has contributed to research in topics: Biology & Medicine. The author has an hindex of 33, co-authored 92 publications receiving 4812 citations. Previous affiliations of Michael Brecht include Humboldt State University & Charité.

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Map plasticity in somatosensory cortex.

TL;DR: Diverse approaches suggest a distributed model in which plasticity occurs at multiple sites in the cortical circuit with multiple cellular/synaptic mechanisms and multiple likely learning rules for plasticity.
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Lentivirus-based genetic manipulations of cortical neurons and their optical and electrophysiological monitoring in vivo

TL;DR: A method for genetic manipulation and subsequent phenotypic analysis of individual cortical neurons in vivo is established and is ideally suited for analysis of gene functions in individual neurons in the intact brain.
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Functional architecture of the mystacial vibrissae.

TL;DR: A synthesis of morphological and behavioral data led to the following functional concept: the mystacial macrovibrissae row is a distance decoder, whose function is to derive head centered obstacle/opening contours at the various dorsoventral angles represented by vibrissal rows.
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Barrel cortex function

TL;DR: It is argued that in order to understand neocortical function one needs to combine a microscopic view, elucidating the workings of the local columnar microcircuits, with a macroscopic view, which keeps track of the linkage of distant cortical modules in different behavioral contexts.
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Intracellular determinants of hippocampal CA1 place and silent cell activity in a novel environment.

TL;DR: In this paper, the authors used whole-cell recording in freely moving rats exploring a novel maze, and observed differences in intrinsic cellular properties and input-based sub-threshold membrane potential levels underlying this division into place and silent cells.