M
Michael F. Hirshman
Researcher at Harvard University
Publications - 143
Citations - 22282
Michael F. Hirshman is an academic researcher from Harvard University. The author has contributed to research in topics: Skeletal muscle & Glucose uptake. The author has an hindex of 65, co-authored 131 publications receiving 20279 citations. Previous affiliations of Michael F. Hirshman include Merck & Co. & Joslin Diabetes Center.
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Contraction stimulates muscle glucose uptake independent of atypical PKC
Haiyan Yu,Nobuharu L. Fujii,Taro Toyoda,Ding An,Robert V. Farese,Michael Leitges,Michael F. Hirshman,Joram D. Mul,Laurie J. Goodyear +8 more
TL;DR: In vitro contraction‐stimulated glucose uptake was greater in soleus muscles of MλKO mice than WT controls, demonstrating that loss of PKC‐λ/ζ activity increases contraction‐ Stimulated muscle glucose uptake.
Journal ArticleDOI
A Novel Role for Adipose Tissue in Exercise‐Induced Improvements in Glucose Homeostasis
Kristin I. Stanford,Roeland J.W. Middelbeek,Ding An,Kristy L. Townsend,Kathleen R. Markan,Kristen M. Hitchcox,Katharina Hellbach,Michael F. Hirshman,Laurie J. Goodyear +8 more
199-OR: Exercise Decreases Mouse and Human Islet Senescence through Glucagon-Mediated AMPK Activation
Priscila Viana Carapeto,Jiho Kahng,Ana B.A. Wagner,Roeland J.W. Middelbeek,Michael F. Hirshman,Laurie J. Goodyear,Cristina Aguayo-Mazzucato +6 more
TL;DR: Exercise has anti-aging effects on mouse and human pancreatic islets by decreasing senescence and improving function and this is a novel mechanism of the effects of exercise on β-cell aging with implications for the treatment of T2D.
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596-P: Exercise Increases Plasma Neuronal Growth Regulator 1 (NEGR1) Concentrations in Human Subjects
Pasquale Nigro,Nicholas P. Carbone,Carlos Roberto Bueno Júnior,Maria Vamvini,Lori Simpson,Michael F. Hirshman,Roeland J.W. Middelbeek,Laurie J. Goodyear +7 more
TL;DR: Middelbeek et al. as discussed by the authors investigated the effects of a single bout of maximal exercise and exercise training on plasma NEGR1 in two different cohorts of obese subjects.