Michael F. Hirshman

TL;DR: In summary, exercise training can overcome high-fat diet-induced impairments in glucose tolerance and increases in adipocyte size, cell number, and fat pad mass and raises the possibility of a specific role of subcutaneous adipose tissue in adaptive responses to exercise training.

TL;DR: It is found that a lack of LKB1 in skeletal muscle enhanced insulin sensitivity, as evidenced by decreased fasting glucose and insulin concentrations, improved glucose tolerance, increased muscle glucose uptake in vivo, and increased glucose utilization during a hyperinsulinemic-euglycemic clamp.

TL;DR: It is concluded that the insulin resistance of the obese rats involves the failure of translocation of transporters, while the action of insulin to increase the average carrier turnover number is normal.

TL;DR: The Molecular Transducers of Physical Activity Consortium (MoTrPAC) will provide a public database that is expected to enhance the understanding of the health benefits of exercise and to provide insight into how physical activity mitigates disease.

TL;DR: The time course of the transport-to-transporter ratio suggests that the intrinsic activity response reverses more rapidly than that involving transporter number, and concludes that the reversal of the increase in glucose uptake by hindquarter skeletal muscle after exercise is correlated with an increase in the glucose transporter number and activity in the plasma membrane.