G
Georges-Philippe Pageaux
Researcher at French Institute of Health and Medical Research
Publications - 12
Citations - 651
Georges-Philippe Pageaux is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Liver transplantation & Transplantation. The author has an hindex of 8, co-authored 12 publications receiving 554 citations. Previous affiliations of Georges-Philippe Pageaux include University of Montpellier.
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Journal ArticleDOI
Sirolimus Use in Liver Transplant Recipients With Hepatocellular Carcinoma: A Randomized, Multicenter, Open-Label Phase 3 Trial
Edward K. Geissler,Andreas A. Schnitzbauer,Andreas A. Schnitzbauer,Carl Zülke,P. Lamby,Andrea Proneth,Christophe Duvoux,Patrizia Burra,Karl-Walter Jauch,Markus Rentsch,Tom M. Ganten,Jan Schmidt,Utz Settmacher,Michael Heise,Michael Heise,Giorgio Rossi,Umberto Cillo,Norman M. Kneteman,René Adam,Bart van Hoek,Philippe Bachellier,Philippe Wolf,Lionel Rostaing,Wolf O. Bechstein,Magnus Rizell,James J. Powell,Ernest Hidalgo,J. Gugenheim,Heiner Wolters,Jens Brockmann,André Roy,Ingrid Mutzbauer,Angela Schlitt,Susanne Beckebaum,Christian Graeb,Silvio Nadalin,Umberto Valente,Victor Sanchez Turrion,Neville V. Jamieson,T. Scholz,Michele Colledan,Fred Fändrich,Thomas Becker,Gunnar Söderdahl,Olivier Chazouillères,Heikki Mäkisalo,Georges-Philippe Pageaux,Rudolf Steininger,Thomas Soliman,Koert P. de Jong,Jacques Pirenne,Raimund Margreiter,Johann Pratschke,Antonio Daniele Pinna,Johann Hauss,Stefan Schreiber,Simone I. Strasser,Jürgen Klempnauer,Roberto Troisi,Sherrie Bhoori,Jan Lerut,Itxarone Bilbao,Christian Klein,Alfred Königsrainer,Darius F. Mirza,Gerd Otto,Vincenzo Mazzaferro,Peter Neuhaus,Hans J. Schlitt +68 more
TL;DR: This trial provides the first high-level evidence base for selecting immunosuppression in LTx recipients with HCC and reveals that low-risk, rather than high- risk, patients benefited most from sirolimus; furthermore, younger recipients (age ⩽60) also benefited, as well siro Limus monotherapy patients.
Journal ArticleDOI
A prospective randomised, open-labeled, trial comparing sirolimus-containing versus mTOR-inhibitor-free immunosuppression in patients undergoing liver transplantation for hepatocellular carcinoma
Andreas A. Schnitzbauer,Carl Zuelke,Christian Graeb,Justine Rochon,Itxarone Bilbao,Patrizia Burra,Koert P. de Jong,Christophe Duvoux,Norman M. Kneteman,René Adam,Wolf O. Bechstein,Thomas Becker,Susanne Beckebaum,Olivier Chazouillères,Umberto Cillo,Michele Colledan,Fred Fändrich,Jean Gugenheim,Johann Hauss,Michael Heise,Ernest Hidalgo,Neville V. Jamieson,Alfred Königsrainer,P. Lamby,Jan Lerut,Heikki Mäkisalo,Raimund Margreiter,Vincenzo Mazzaferro,Ingrid Mutzbauer,Gerd Otto,Georges-Philippe Pageaux,Antonio Daniele Pinna,Jacques Pirenne,Magnus Rizell,Giorgio Rossi,Lionel Rostaing,André Roy,Victor Sanchez Turrion,Jan Schmidt,Roberto Troisi,Bart van Hoek,Umberto Valente,Philippe Wolf,Heiner Wolters,Darius F. Mirza,T. Scholz,Rudolf Steininger,Gunnar Söderdahl,Simone I. Strasser,Karl-Walter Jauch,Peter Neuhaus,Hans J. Schlitt,Edward K Geissler +52 more
TL;DR: If the hypothesis is correct that mTOR inhibition can reduce HCC tumour growth while simultaneously providing immunosuppression to protect the liver allograft from rejection, patients should experience less post-transplant problems with HCC recurrence, and therefore could expect a longer and better quality of life.
Journal ArticleDOI
Transplantation for acute liver failure in patients exposed to NSAIDs or paracetamol (acetaminophen): the multinational case-population SALT study.
Sinem Ezgi Gulmez,Sinem Ezgi Gulmez,Dominique Larrey,Georges-Philippe Pageaux,Séverine Lignot,Séverine Lignot,Régis Lassalle,Régis Lassalle,Jérémy Jové,Jérémy Jové,Angelo Gatta,P. Aiden McCormick,Harold J. Metselaar,Estela Monteiro,Douglas Thorburn,William Bernal,Irene Zouboulis-Vafiadis,Corinne S de Vries,Susana Perez-Gutthann,Miriam C. J. M. Sturkenboom,Jacques Benichou,Jean-Louis Montastruc,Yves Horsmans,Francesco Salvo,F. Hamoud,F. Hamoud,S. Micon,S. Micon,Cécile Droz-Perroteau,Cécile Droz-Perroteau,Patrick Blin,Patrick Blin,Nicholas Moore,Nicholas Moore +33 more
TL;DR: ALF leading to registration for transplantation after exposure to an NSAID was rare, with no major difference between NSAID and paracetamol.
Journal ArticleDOI
Comparison of serum HBsAg quantitation by four immunoassays, and relationships of HBsAg level with HBV replication and HBV genotypes.
Edouard Tuaillon,Anne-Marie Mondain,Nicolas Nagot,Laure Ottomani,Dramane Kania,Erika Nogue,Pierre-Alain Rubbo,Georges-Philippe Pageaux,Philippe Van de Perre,Jacques Ducos +9 more
TL;DR: The quantitation of HBsAg in routine clinical samples is comparable between the reference assay and the adapted assays with acceptable accuracy limits, low levels of variability and minimum discrepancy.
Journal ArticleDOI
Quality of life in patients with chronic hepatitis C infection: Severe comorbidities and disease perception matter more than liver-disease stage.
Sabrina Cossais,Michaël Schwarzinger,Stanislas Pol,Hélène Fontaine,Dominique Larrey,Georges-Philippe Pageaux,Valérie Canva,Philippe Mathurin,Yazdan Yazdanpanah,Sylvie Deuffic-Burban,Sylvie Deuffic-Burban +10 more
TL;DR: The presence of severe comorbidities and worrying about CHC progression, but not stage of fibrosis, seem to alter significantly EQ-5D health utility in CHC French patients.