M
Michael McClelland
Researcher at University of California, Irvine
Publications - 376
Citations - 29109
Michael McClelland is an academic researcher from University of California, Irvine. The author has contributed to research in topics: Salmonella enterica & Salmonella. The author has an hindex of 79, co-authored 372 publications receiving 27627 citations. Previous affiliations of Michael McClelland include University of Illinois at Chicago & University of Georgia.
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Journal ArticleDOI
Fingerprinting genomes using PCR with arbitrary primers
John Welsh,Michael McClelland +1 more
TL;DR: The generality of the arbitrarily primed PCR method is demonstrated by application to twenty four strains from five species of Staphylococcus, eleven strains of Streptococcus pyogenes and three varieties of Oryza sativa.
Journal ArticleDOI
Complete genome sequence of Salmonella enterica serovar Typhimurium LT2
Michael McClelland,Kenneth E. Sanderson,John Spieth,Sandra W. Clifton,Phil Latreille,Laura Courtney,Steffen Porwollik,Johar Ali,Mike Dante,Feiyu Du,Shunfang Hou,Dan Layman,Shawn Leonard,Christine Nguyen,Kelsi Scott,Andrea Holmes,Neenu Grewal,Elizabeth Mulvaney,Ellen E. Ryan,Hui Sun,Liliana Florea,Liliana Florea,Webb Miller,Tamberlyn Stoneking,Michael Nhan,Robert H. Waterston,Richard K. Wilson +26 more
TL;DR: The distribution of close homologues of S. typhimurium LT2 genes in eight related enterobacteria was determined using previously completed genomes of three related bacteria, sample sequencing of both S. enterica serovar Paratyphi A and Klebsiella pneumoniae as mentioned in this paper.
Journal ArticleDOI
Selective silencing of foreign DNA with low GC content by the H-NS protein in Salmonella.
William Wiley Navarre,Steffen Porwollik,Yipeng Wang,Michael McClelland,Henry Rosen,Stephen J. Libby,Ferric C. Fang +6 more
TL;DR: H-NS provides a previously unrecognized mechanism of bacterial defense against foreign DNA, enabling the acquisition of DNA from exogenous sources while avoiding detrimental consequences from unregulated expression of newly acquired genes.
Journal ArticleDOI
Arbitrarily primed PCR fingerprinting of RNA.
TL;DR: Fingerprinting of RNA populations was achieved using an arbitrarily selected primer at low stringency for first and second strand cDNA synthesis and PCR amplification was then used to amplify the products.
Journal ArticleDOI
Effect of site-specific modification on restriction endonucleases and DNA modification methyltransferases.
TL;DR: A table of known site-specific DNA modification methyltransferases and their specificities is presented along with EMBL database accession numbers for cloned genes.