Michael McClelland

TL;DR: A new transcriptional regulation pathway is uncovered in which the Cpx envelope stress response system modulates the integrity of the cell envelope in part by controlling peptidoglycan amidase activity, which confers bacterial resistance to protamine and α-helical CAMPs.

TL;DR: Four large gene expression microarray data sets from prostate cancer, whose tissue components were estimated by pathologists, were used to test the performance of multivariate linear regression models for in silico prediction of major tissue components.

TL;DR: An updated list of the sensitivities of over 240 restriction endonucleases to the site-specific DNA modifications '14C, n-6C, h1"5C, and m6A, four modifications that are common in DNA prokaryotes, eukaryote, and their viruses is presented.

TL;DR: The findings indicate the involvement of a relatively small fraction of the Salmonella genome in transcriptional adjustment from water to dehydration, with a high prevalence of genes belonging to the protein biosynthesis machinery.

TL;DR: The megaplasmids and the chromosome from the bacterium Rhizobium meliloti 1021 were separated in preparative quantities by using transverse alternating-field gel electrophoresis and the genetic content of each electrophoretically separated band was determined by Southern hybridization with replicon-specific probes and by comparison with Agrobacterium tumefaciens transconjugants harboring either pSym-a or p Sym-b megaplasmaids.