M
Michael McClelland
Researcher at University of California, Irvine
Publications - 376
Citations - 29109
Michael McClelland is an academic researcher from University of California, Irvine. The author has contributed to research in topics: Salmonella enterica & Salmonella. The author has an hindex of 79, co-authored 372 publications receiving 27627 citations. Previous affiliations of Michael McClelland include University of Illinois at Chicago & University of Georgia.
Papers
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Journal ArticleDOI
The wisdom of the commons
James A. Koziol,Anne C. Feng,Zhenyu Jia,Yipeng Wang,Seven Goodison,Michael McClelland,Dan Mercola +6 more
TL;DR: Using time to progression following prostatectomy as the relevant clinical endpoint, it was found that ensemble tree classifiers robustly and reproducibly identified three subgroups of patients in the two clinical datasets: non-progressors, early progressors and late progressors.
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Identification and characterization of Cronobacter iron acquisition systems.
Christopher J. Grim,Mahendra H. Kothary,Gopal R. Gopinath,K. G. Jarvis,J. Jean-Gilles Beaubrun,Michael McClelland,Ben D. Tall,A. A. Franco +7 more
TL;DR: Results support the proposition that C. sakazakii and C. malonaticus may be more associated with the human host than previously thought, and iron acquisition systems in 231 Cronobacter strains isolated from different sources were identified and characterized.
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Site-specific cleavage of DNA at 8- and 10-base-pair sequences.
TL;DR: It is described how the above technique can be extended to generate Dpn I cleavage sites of up to 12 base pairs, and potential applications, including the development of cloning vectors and a rapid method for chromosome walking, are discussed.
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Nitric Oxide Antagonizes the Acid Tolerance Response that Protects Salmonella against Innate Gastric Defenses
Travis J. Bourret,Steffen Porwollik,Michael McClelland,Rui Zhao,Todd M. Greco,Harry Ischiropoulos,Andrés Vázquez-Torres +6 more
TL;DR: The RNS-mediated inhibition of the Salmonella ATR described herein may represent a common component of innate host defenses, suggesting that RNS target regulatory cascades but not their effectors.
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Activity of DNA modification and restriction enzymes in KGB, a potassium glutamate buffer.
John Hanish,Michael McClelland +1 more
TL;DR: A single buffer consisting primarily of potassium and glutamate is shown to be suitable for activity of almost all restriction endonucleases, DNA methylases, and many other DNA-modifying enzymes.