M
Michael McClelland
Researcher at University of California, Irvine
Publications - 376
Citations - 29109
Michael McClelland is an academic researcher from University of California, Irvine. The author has contributed to research in topics: Salmonella enterica & Salmonella. The author has an hindex of 79, co-authored 372 publications receiving 27627 citations. Previous affiliations of Michael McClelland include University of Illinois at Chicago & University of Georgia.
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Journal ArticleDOI
The small RNA RyhB homologs from Salmonella typhimurium participate in the response to S-nitrosoglutathione-induced stress.
Paulina F. Calderón,Eduardo H. Morales,Lillian G. Acuña,Danitza N. Fuentes,Fernando Gil,Steffen Porwollik,Michael McClelland,Claudia P. Saavedra,Iván L. Calderón +8 more
TL;DR: Together, these results suggest that RyhB-1 and RyHB-2 finely tune the expression of genes coding for cytochrome oxidases and the nitrate reductase system, allowing the cell to cope with GSNO-induced stress.
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Increased HDAC1 deposition at hematopoietic promoters in AML and its association with patient survival
Lara Tickenbrock,Lara Tickenbrock,Hans-Ulrich Klein,Cristina Trento,Antje Hascher,Stefanie Göllner,Nicole Bäumer,Robert Kuss,Shuchi Agrawal,Gesine Bug,Hubert Serve,Christian Thiede,Gerhard Ehninger,Udo zur Stadt,Michael McClelland,Yipeng Wang,Anke Becker,Steffen Koschmieder,Wolfgang E. Berdel,Martin Dugas,Carsten Müller-Tidow +20 more
TL;DR: This is the first study to determine HDAC1 modification patterns in a large number of AML and ALL specimens and suggests that dyslocalization of HDAC 1 is a common feature in AML.
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Kinesin-like protein CENP-E is upregulated in rheumatoid synovial fibroblasts
Frank Kullmann,Martin Judex,Wibke Ballhorn,Hans-Peter Jüsten,Wessinghage D,John Welsh,Tim J. Yen,Bernhard Lang,Jim C Hittle,Michael McClelland,Jürgen Schölmerich,Ulf Müller-Ladner +11 more
TL;DR: RAP-PCR is a suitable method to identify differentially expressed genes in rheumatoid synovial fibroblasts and because motifs of CENP-E show homologies to jun and fos oncogene products and are involved in virus assembly, CENp-E may be involved in the pathophysiology of RA.
Journal ArticleDOI
Virulence of 32 Salmonella Strains in Mice
Matthew C. Swearingen,Steffen Porwollik,Prerak T. Desai,Michael McClelland,Brian M. M. Ahmer +4 more
TL;DR: Onlyserovar Paratyphi C strain BAA1715 and serovar Typhimurium strain 14028 were fully virulent in mice and none of the strains tested provided immunity to TyphIMurium infection.
Journal ArticleDOI
Multicopy Single-Stranded DNA Directs Intestinal Colonization of Enteric Pathogens
Johanna R. Elfenbein,Leigh A. Knodler,Ernesto S. Nakayasu,Charles Ansong,Heather M. Brewer,Lydia M. Bogomolnaya,L. Garry Adams,Michael McClelland,Joshua N. Adkins,Helene Andrews-Polymenis +9 more
TL;DR: It is concluded that a natural function of msDNA is to regulate protein abundance, the first attributable function for any msDNA, and provides novel insight into the function of this mysterious molecule that likely represents a new class of regulatory molecules.