M
Michael Sommerauer
Researcher at Aarhus University Hospital
Publications - 17
Citations - 878
Michael Sommerauer is an academic researcher from Aarhus University Hospital. The author has contributed to research in topics: Parkinson's disease & REM sleep behavior disorder. The author has an hindex of 8, co-authored 17 publications receiving 430 citations. Previous affiliations of Michael Sommerauer include University of Cologne & Forschungszentrum Jülich.
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Journal ArticleDOI
Brain-first versus body-first Parkinson’s disease: a multimodal imaging case-control study
Jacob Horsager,Katrine B. Andersen,Karoline Knudsen,Casper Skjærbæk,Tatyana D. Fedorova,Niels Okkels,Eva Schaeffer,Sarah K Bonkat,Jacob Geday,Marit Otto,Michael Sommerauer,Erik H. Danielsen,Einar Bech,Jonas Kraft,Ole Lajord Munk,Sandra D Hansen,Nicola Pavese,Nicola Pavese,Robert Göder,David J. Brooks,David J. Brooks,Daniela Berg,Per Borghammer +22 more
TL;DR: The existence of brain-first and body-first subtypes of Parkinson's disease is supported by quantifying neuronal dysfunction in structures corresponding to Braak stages I, II and III involvement in three distinct patient groups using multimodal imaging.
Journal ArticleDOI
In-vivo staging of pathology in REM sleep behaviour disorder: a multimodality imaging case-control study
Karoline Knudsen,Tatyana D. Fedorova,Allan K Hansen,Michael Sommerauer,Marit Otto,Kristina Bacher Svendsen,Adjmal Nahimi,Morten Gersel Stokholm,Nicola Pavese,Nicola Pavese,Nicola Pavese,Christoph P. Beier,David J. Brooks,David J. Brooks,David J. Brooks,Per Borghammer +15 more
TL;DR: Patients with idiopathic REM sleep behaviour disorder had fully developed pathology in the peripheral autonomic nervous system and the locus coeruleus, equal to that in diagnosed Parkinson's disease.
Journal ArticleDOI
Evaluation of the noradrenergic system in Parkinson's disease: an 11C-MeNER PET and neuromelanin MRI study.
Michael Sommerauer,Tatyana D. Fedorova,Allan K Hansen,Karoline Knudsen,Marit Otto,Jesper Jeppesen,Yoon Frederiksen,Jakob Udby Blicher,Jacob Geday,Adjmal Nahimi,Malene Flensborg Damholdt,David J. Brooks,David J. Brooks,David J. Brooks,Per Borghammer +14 more
TL;DR: Reduced noradrenergic function in Parkinson's disease was linked to the presence of RBD and associated with cognitive deterioration and orthostatic hypotension and may be of relevance when treating these conditions in Parkinson’s disease.
Journal ArticleDOI
Does inflammation precede tau aggregation in early Alzheimer's disease? A PET study
Peter Parbo,Rola Ismail,Michael Sommerauer,Morten Gersel Stokholm,Allan K Hansen,Kim V. Hansen,Ali Amidi,Jeppe L. Schaldemose,Hanne Gottrup,Hans Brændgaard,Simon Fristed Eskildsen,Per Borghammer,Rainer Hinz,Joel Aanerud,David J. Brooks,David J. Brooks +15 more
TL;DR: The temporal and spatial inter-relationships between levels of cortical microglial activation and the aggregated amyloid-β and tau load in mild cognitive impairment (MCI) and early Alzheimer's disease (AD) were assessed with positron emission tomography.
Journal ArticleDOI
Noradrenergic Deficits in Parkinson Disease Imaged with 11C-MeNER.
Adjmal Nahimi,Michael Sommerauer,Martin B. Kinnerup,Karen Østergaard,Michael Wintherdahl,Jan Jacobsen,Anna C. Schacht,Birger Johnsen,Malene Flensborg Damholdt,Per Borghammer,Albert Gjedde +10 more
TL;DR: A decline of noradrenergic projections in vivo in brain of PD patients is discovered, the first specific quantification of nor adrenergic denervation in PD patients in vivo, and predicted from determinations in vitro.