M
Michele Caraglia
Researcher at Seconda Università degli Studi di Napoli
Publications - 562
Citations - 24508
Michele Caraglia is an academic researcher from Seconda Università degli Studi di Napoli. The author has contributed to research in topics: Cancer & Cancer cell. The author has an hindex of 67, co-authored 525 publications receiving 20615 citations. Previous affiliations of Michele Caraglia include Temple University & Magna Græcia University.
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Journal ArticleDOI
DTNQ-Pro, a Mimetic Dipeptide, Sensitizes Human Colon Cancer Cells to 5-Fluorouracil Treatment
Isabel Gomez-Monterrey,Pietro Campiglia,Ilaria Scognamiglio,Daniela Vanacore,Alessandra Dicitore,Angela Lombardi,Michele Caraglia,Ettore Novellino,Paola Stiuso +8 more
TL;DR: This study evaluated whether a decrease of stress proteins induced by DTNQ-Pro in Caco-2 cells could sensitize these cells to treatment with 5-fluorouracil (5-FU) cytotoxicity, which could cause the sensitization of cancer cells to the cytot toxicity mediated by 5-FU.
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New Therapeutic Opportunities from Old Drugs: The Role of Nanotechnology?
TL;DR: This article was originally published in a journal by OMICS Publishing Group, and the attached copy is provided by the author for the author's benefit and for the benefit of the author’s institution.
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Exploring the efficacy and safety of single-agent sorafenib in a cohort of Italian patients with hepatocellular carcinoma.
Daniele Santini,Raffaele Addeo,Bruno Vincenzi,Alice Calvieri,Liliana Montella,Marianna Silletta,Michele Caraglia,Umberto Vespasiani,Antonio Picardi,Salvatore Del Prete,Giuseppe Tonini +10 more
TL;DR: Although the retrospective design of this study does not allow reaching any definite conclusion, the results could lend some preliminary support to the safety and the effectiveness of sorafenib monotherapy in patients with Child–Pugh B and Child-Pugh C liver function.
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HtrA1 loss is related to aggressive behavior parameters in sentinel node positive breast cancer.
Renato Franco,Francesca Collina,Maurizio Di Bonito,Gerardo Botti,Donatella Montanaro,Luigi Di Maio,Bruno Vincenzi,G. Landi,Massimiliano D’Aiuto,Michele Caraglia,Alfonso Baldi +10 more
TL;DR: Low HtrA1 expression is significantly related to breast cancer poor prognosis parameters, and H trA1 loss in sentinel nodes is related to metastasis of non sentinel node, offering a further marker useful for BC prognostic stratification.
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Prognostic significance of cxcr4 in colorectal cancer: An updated meta-analysis and critical appraisal
Alessandro Ottaiano,Mariachiara Santorsola,Paola Del Prete,Francesco Perri,Stefania Scala,Michele Caraglia,Guglielmo Nasti +6 more
TL;DR: In this paper, the authors provided an updated estimate of the prognostic power of C-X-C chemokine receptor type 4 (CXCR4) in colorectal cancer (CRC), and analyzed modalities of evaluating and reporting its expression.