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Michele Caraglia

Researcher at Seconda Università degli Studi di Napoli

Publications -  562
Citations -  24508

Michele Caraglia is an academic researcher from Seconda Università degli Studi di Napoli. The author has contributed to research in topics: Cancer & Cancer cell. The author has an hindex of 67, co-authored 525 publications receiving 20615 citations. Previous affiliations of Michele Caraglia include Temple University & Magna Græcia University.

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Journal Article

Intraluminal gel ultrasound and eco-color doppler: new tools for the study of colorectal cancer in mice.

TL;DR: Ulster is a rapid examination compared to other diagnostic techniques that has a good sensitivity when the tumours reach the dimensions of 3 mm² or more and is able to detect only tumours with sizes ≥3 mm².
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A novel metronomic schedule of oral vinorelbine for the treatment of metastatic breast cancer in elderly patients: A phase II trial

TL;DR: Metronomic oral VNR can be safely administered to elderly patients with MBC and is active in this population, and the schedule was well tolerated.
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Highlights of the Annual Meeting of the Italian Association for Cell Cultures (AICC): new drug delivery strategies and technological platforms for diagnosis and therapy of tumors. Part II. 6 - 7 December 2007, Naples, Italy.

TL;DR: The crossing of the blood–brain barrier by pegylated liposomes in order to deliver antitumor drugs to brain tumor sites was explored and the pharmacokinetics and pharmaco-distribution of different carrier systems were explained.
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Up-regulated EGF receptors undergo to rapid internalization and ubiquitin-dependent degradation in human cancer cells exposed to 8-Cl-cAMP

TL;DR: Analysis of epidermal growth factor‐dependent receptor internalization in 8‐Cl‐cAMP‐treated cells showed a higher endocytosis rate as well as an accelerated degradation which occurred together with an increased receptor ubiquitination, suggesting its combination with agents that disrupt epiderm growth factor receptor signalling.