M
Michele Caraglia
Researcher at Seconda Università degli Studi di Napoli
Publications - 562
Citations - 24508
Michele Caraglia is an academic researcher from Seconda Università degli Studi di Napoli. The author has contributed to research in topics: Cancer & Cancer cell. The author has an hindex of 67, co-authored 525 publications receiving 20615 citations. Previous affiliations of Michele Caraglia include Temple University & Magna Græcia University.
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Journal ArticleDOI
Bax mutation and overexpression inversely correlate with immature phenotype and prognosis of childhood germ cell tumors
Raffaele Addeo,Stefania Crisci,Velia D'Angelo,Bruno Vincenzi,Fiorina Casale,Guido Pettinato,Vittoria Donofrio,Renata Boldrini,Rita Alaggio,Paola Collini,Roberta Bertorelle,Maria Teresa Di Tullio,Michele Caraglia,Monica Terenziani,Margherita Lo Curto,Paolo Indolfi +15 more
TL;DR: Results indicate that both mutations and BAX protein levels are useful molecular biological markers for prognosis and clinical management of pediatric GCT.
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Could PD-1/PDL1 immune checkpoints be linked to HLA signature?
Pierpaolo Correale,Rita Emilena Saladino,Valerio Nardone,Rocco Giannicola,Rita Agostino,Luigi Pirtoli,Michele Caraglia,Ciro Botta,Pierosandro Tagliaferri +8 more
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Dissecting the prevention of estrogen-dependent breast carcinogenesis through Nrf2-dependent and independent mechanisms.
Aldo Giudice,Antonio Barbieri,Sabrina Bimonte,Marco Cascella,Arturo Cuomo,Anna Crispo,Giovanni D'Arena,Massimiliano Galdiero,Maria Elena Della Pepa,Gerardo Botti,Michele Caraglia,Mario Capunzo,Claudio Arra,Maurizio Montella +13 more
TL;DR: The use of specific phytochemicals and dietary supplements can inhibit the risk of breast cancer not only by the modulation of several estrogen-activating enzymes but also through the induction of various cytoprotective enzymes that reestablish the homeostatic balance of estrogen metabolism via nuclear factor erythroid 2-related factor 2 (Nrf2)-dependent and independent mechanisms.
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Urotensin-II-Targeted Liposomes as a New Drug Delivery System towards Prostate and Colon Cancer Cells.
Silvia Zappavigna,Marianna Abate,Alessia Maria Cossu,Sara Lusa,Virginia Campani,Lorena Scotti,Amalia Luce,Ali Munaim Yousif,Francesco Merlino,Paolo Grieco,Giuseppe De Rosa,Michele Caraglia +11 more
TL;DR: Developing liposomes conjugated with UT-II (LipoUT) for efficient targeting of cancer cells that overexpress UTR potentiated its delivery in UTR-overexpressing cells and could represent a new tool for the targeting of prostate and colon cancer.
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Microsatellite Instability: From the Implementation of the Detection to a Prognostic and Predictive Role in Cancers
Martina Amato,Renato Franco,Gaetano Facchini,Raffaele Addeo,Fortunato Ciardiello,Massimiliano Berretta,Giulia Vita,Alessandro Sgambato,Sandro Pignata,Michele Caraglia,Marina Accardo,Federica Zito Marino +11 more
TL;DR: An overview of MSI in various cancer types, highlighting its potential predictive/prognostic role and the clinical trials performed is provided and the comparison data between the different assays used to detect MSI in clinical practice is focused on.