M
Mikael Mazighi
Researcher at University of Paris
Publications - 301
Citations - 12620
Mikael Mazighi is an academic researcher from University of Paris. The author has contributed to research in topics: Stroke & Modified Rankin Scale. The author has an hindex of 48, co-authored 249 publications receiving 9611 citations. Previous affiliations of Mikael Mazighi include Cleveland Clinic & University of Toronto.
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Journal ArticleDOI
Ferumoxtran-10–Enhanced MRI of the Hypercholesterolemic Rabbit Aorta Relationship Between Signal Loss and Macrophage Infiltration
Fabien Hyafil,Jean-Pierre Laissy,Mikael Mazighi,Didier Tchetche,Liliane Louedec,Homa Adle-Biassette,Sylvie Chillon,Dominique Hénin,Marie-Paule Jacob,Didier Letourneur,Laurent J. Feldman +10 more
TL;DR: Ferumoxtran-10–enhanced MRI allows quantitative assessment of macrophage infiltration induced by balloon angioplasty in the aorta of hypercholesterolemic rabbits.
Journal ArticleDOI
Mechanical thrombectomy in basilar artery occlusion: influence of reperfusion on clinical outcome and impact of the first-line strategy (ADAPT vs stent retriever).
Benjamin Gory,Mikael Mazighi,Raphaël Blanc,Julien Labreuche,Michel Piotin,Francis Turjman,Bertrand Lapergue +6 more
TL;DR: Mmong BAO patients, successful reperfusion is a strong predictor of a 90-day favorable outcome, and the choice of ADAPT as the first-line strategy achieves a significantly higher rate of complete reperfusions with a shorter procedure duration.
Journal ArticleDOI
Successful Reperfusion With Mechanical Thrombectomy Is Associated With Reduced Disability and Mortality in Patients With Pretreatment Diffusion-Weighted Imaging–Alberta Stroke Program Early Computed Tomography Score ≤6
Jean-Philippe Desilles,Arthuro Consoli,H Redjem,Oguzhan Coskun,Gabriele Ciccio,Stanislas Smajda,Julien Labreuche,Cristian Preda,Clara Ruiz Guerrero,Jean-Pierre Decroix,G. Rodesch,Mikael Mazighi,Raphaël Blanc,Michel Piotin,Bertrand Lapergue +14 more
TL;DR: Successful reperfusion is associated with reduced mortality and disability in patients with a pretreatment DWI-ASPECTS ⩽6, and further data from randomized studies are needed.
Journal ArticleDOI
Safety and efficacy of intensive blood pressure lowering after successful endovascular therapy in acute ischaemic stroke (BP-TARGET): a multicentre, open-label, randomised controlled trial.
Mikael Mazighi,Sébastien Richard,Bertrand Lapergue,Igor Sibon,Benjamin Gory,Jérôme Berge,Arturo Consoli,Julien Labreuche,Jean-Marc Olivot,Joseph P. Broderick,Alain Duhamel,Emmanuel Touzé,Adnan I Qureshi,Amélie Yavchitz,Simon Escalard,Jean-Philippe Desilles,Hocine Redjem,Stanislas Smajda,Robert Fahed,Solène Hebert,Benjamin Maïer,François Delvoye,Perrine Boursin,Malek Ben Maacha,Michael Obadia,Candice Sabben,Raphaël Blanc,Julien Savatovsky,Michel Piotin,Alexandre Obadia,Igor Raynouard,Erwan Morvan,Adrien Wang,Gioia Mione,Lisa Humbertjean,Matthieu Bonnerot,Jean-Christophe Lacour,René Anxionnat,Romain Tonnelet,Serge Bracard,Xavier Barreau,Gaultier Marnat,Ludovic Lucas,Pauline Renou,Sabrina Debruxelles,Mathilde Poli,Sharmila Sagnier +46 more
TL;DR: The BP-TARGET trial as mentioned in this paper showed that a target of 100-129 mm Hg after successful endovascular therapy did not reduce radiographic intraparenchymal haemorrhage rates at 24-36 h as compared with a standard care systolic blood pressure target of 130-185 mm HG.
Journal ArticleDOI
Mortality and Disability According to Baseline Blood Pressure in Acute Ischemic Stroke Patients Treated by Thrombectomy: A Collaborative Pooled Analysis.
Benjamin Maïer,Benjamin Gory,Guillaume Taylor,Julien Labreuche,Raphaël Blanc,Michael Obadia,Marie Abrivard,Stanislas Smajda,Jean-Philippe Desilles,Hocine Redjem,Gabriele Ciccio,Anne Claire Lukaszewicz,Francis Turjman,Roberto Riva,Paul Emile Labeyrie,Alain Duhamel,Jacques Blacher,Michel Piotin,Bertrand Lapergue,Mikael Mazighi +19 more
TL;DR: In acute ischemic stroke patients treated by mechanical thrombectomy, baseline SBP is associated with all‐cause mortality and favorable outcome, and in contrast to mortality, favorable outcome rate was the highest at low SBP values and lowest at highSBP values.