M
Mikael Sjölinder
Researcher at Karolinska Institutet
Publications - 11
Citations - 1249
Mikael Sjölinder is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: Leukotriene & Leukotriene C4. The author has an hindex of 9, co-authored 11 publications receiving 1151 citations. Previous affiliations of Mikael Sjölinder include Uppsala University.
Papers
More filters
Journal ArticleDOI
Circular chromosome conformation capture (4C) uncovers extensive networks of epigenetically regulated intra-and interchromosomal interactions
Zhihu Zhao,Gholamreza Tavoosidana,Mikael Sjölinder,Anita Göndör,Piero Mariano,Sha Wang,Chandrasekhar Kanduri,Magda Lezcano,Kuljeet Singh Sandhu,Umashankar Singh,Vinod Pant,Vijay K. Tiwari,Sreenivasulu Kurukuti,Rolf Ohlsson +13 more
TL;DR: It is found that the direct interaction between differentially methylated regions was linked to epigenetic regulation of transcription in trans and the patterns of interactions specific to the maternal H19 imprinting control region underwent reprogramming during in vitro maturation of embryonic stem cells.
Journal ArticleDOI
Nonallelic transvection of multiple imprinted loci is organized by the H19 imprinting control region during germline development.
Kuljeet Singh Sandhu,Chengxi Shi,Mikael Sjölinder,Zhihu Zhao,Anita Göndör,Liang Liu,Vijay K. Tiwari,Sylvain Guibert,Lina Emilsson,Marta P. Imreh,Rolf Ohlsson +10 more
TL;DR: A network of physically juxtaposed regions from the entire genome with the common denominator of being genomically imprinted is identified, concluding that one locus can directly or indirectly influence epigenetic states of multiple regions on other chromosomes with which it interacts.
Journal ArticleDOI
Expression of mRNA encoding neurotrophins and neurotrophin receptors in human granulocytes and bone marrow cells--enhanced neurotrophin-4 expression induced by LTB4.
Maria Assunta Laurenzi,Tommaso Beccari,Leif Stenke,Mikael Sjölinder,Sofia Stinchi,Jan Åke Lindgren +5 more
TL;DR: The results suggest that neurotrophins may act as granulocyte‐derived effector molecules and that human bone marrow cells may be targets for these compounds, in particular BDNF and NT‐4.
Journal ArticleDOI
Characterization of a leukotriene C4 export mechanism in human platelets: possible involvement of multidrug resistance-associated protein 1.
TL;DR: The presence in platelets of multidrug resistance-associated protein 1 (MRP1), a protein described to be an energy-dependent LTC4 transporter in various cell types, was demonstrated at the mRNA and protein level and further support the physiological relevance of platelet L TC4 production.
Journal ArticleDOI
Demonstration of leukotriene‐C4 synthase in platelets and species distribution of the enzyme activity
Susanne Tornhamre,Mikael Sjölinder,Åsa Lindberg,Inger Ericsson,Barbro Näsman-Glaser,William J. Griffiths,Jan Åke Lindgren +6 more
TL;DR: It is established that platelets contain LTC4 synthase and indicates that this enzyme is widely distributed among platelets from various species.