M
Miklos Espak
Researcher at University College London
Publications - 7
Citations - 724
Miklos Espak is an academic researcher from University College London. The author has contributed to research in topics: Neuropsychology & Frontotemporal dementia. The author has an hindex of 7, co-authored 7 publications receiving 556 citations. Previous affiliations of Miklos Espak include UCL Institute of Neurology.
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Journal ArticleDOI
Presymptomatic cognitive and neuroanatomical changes in genetic frontotemporal dementia in the Genetic Frontotemporal dementia Initiative (GENFI) study: a cross-sectional analysis
Jonathan D. Rohrer,Jennifer M. Nicholas,Jennifer M. Nicholas,David M. Cash,John C. van Swieten,Elise G.P. Dopper,Lize C. Jiskoot,Rick van Minkelen,Serge A.R.B. Rombouts,M. Jorge Cardoso,Shona Clegg,Miklos Espak,Simon Mead,David L. Thomas,Enrico De Vita,Mario Masellis,Sandra E. Black,Morris Freedman,Ron Keren,Bradley J. MacIntosh,Ekaterina Rogaeva,David F. Tang-Wai,Maria Carmela Tartaglia,Robert Laforce,Fabrizio Tagliavini,Pietro Tiraboschi,Veronica Redaelli,Sara Prioni,Marina Grisoli,Barbara Borroni,Alessandro Padovani,Daniela Galimberti,Elio Scarpini,Andrea Arighi,Giorgio G. Fumagalli,James B. Rowe,Ian Coyle-Gilchrist,Caroline Graff,Caroline Graff,Marie Fallström,Vesna Jelic,Vesna Jelic,Anne Kinhult Ståhlbom,Anne Kinhult Ståhlbom,Christin Andersson,Christin Andersson,Håkan Thonberg,Håkan Thonberg,Lena Lilius,Giovanni B. Frisoni,Giuliano Binetti,Michela Pievani,Martina Bocchetta,Luisa Benussi,Roberta Ghidoni,Elizabeth Finger,Sandro Sorbi,Benedetta Nacmias,Gemma Lombardi,Cristina Polito,Jason D. Warren,Sebastien Ourselin,Nick C. Fox,Martin N. Rossor +63 more
TL;DR: Structural imaging and cognitive changes can be identified 5-10 years before expected onset of symptoms in asymptomatic adults at risk of genetic frontotemporal dementia, which could help to define biomarkers that can stage presymPTomatic disease and track disease progression.
Journal ArticleDOI
Study protocol: Insight 46 – a neuroscience sub-study of the MRC National Survey of Health and Development
Christopher A. Lane,Thomas D. Parker,Dave Cash,Kirsty Macpherson,Elizabeth Donnachie,Heidi Murray-Smith,Anna Barnes,Suzie Barker,Daniel Beasley,Jose Bras,Jose Bras,David Brown,Ninon Burgos,Michelle Byford,M. Jorge Cardoso,Ana Sofia Carvalho,Jessica D. Collins,Enrico De Vita,John Dickson,Norah Epie,Miklos Espak,Susie M.D. Henley,Chandrashekar Hoskote,Michael Hütel,Jana Klimova,Ian B. Malone,Pawel J. Markiewicz,Andrew Melbourne,Marc Modat,Anette Schrag,Sachit Shah,Nikhil Sharma,Carole H. Sudre,David L. Thomas,Andrew Wong,Hui Zhang,John Hardy,Henrik Zetterberg,Henrik Zetterberg,Henrik Zetterberg,Sebastien Ourselin,Sebastian J. Crutch,Diana Kuh,Marcus Richards,Nick C. Fox,Jonathan M. Schott +45 more
TL;DR: The sub-study design and protocol involves a prospective two time-point data collection covering clinical, neuropsychological, β-amyloid positron emission tomography and magnetic resonance imaging, biomarker and genetic information, which will provide an evidence base for the rational design of disease-modifying trials.
Journal ArticleDOI
Automated hippocampal segmentation in patients with epilepsy: available free online.
Gavin P. Winston,M. Jorge Cardoso,E. Williams,Jane L. Burdett,Philippa A. Bartlett,Miklos Espak,Charles Behr,John S. Duncan,Sebastien Ourselin +8 more
TL;DR: This work validate and make freely available online a novel automated method for hippocampal volumetry that performs well in patients with temporal lobe epilepsy and performs poorly in automated algorithms.
Journal ArticleDOI
Detailed volumetric analysis of the hypothalamus in behavioral variant frontotemporal dementia
Martina Bocchetta,Martina Bocchetta,Elizabeth Gordon,Emily N. Manning,Josephine Barnes,David M. Cash,Miklos Espak,Miklos Espak,David L. Thomas,Marc Modat,Marc Modat,Martin N. Rossor,Jason D. Warren,Sebastien Ourselin,Sebastien Ourselin,Giovanni B. Frisoni,Jonathan D. Rohrer +16 more
TL;DR: Patients with bvFTD patients had lower hypothalamic volumes compared with controls, and different genetic mutations may have a differential impact on the hypothalamus.
Journal ArticleDOI
The NifTK software platform for image-guided interventions: platform overview and NiftyLink messaging.
Matthew J. Clarkson,Gergely Zombori,Steve Thompson,Johannes Totz,Yi Song,Miklos Espak,Stian Flage Johnsen,David J. Hawkes,Sebastien Ourselin +8 more
TL;DR: These packages form part of the NifTK platform and have proven to be successful in a variety of image-guided surgery projects and are provided open-source under a BSD license.