M
Milton P. Gordon
Researcher at University of Washington
Publications - 185
Citations - 16455
Milton P. Gordon is an academic researcher from University of Washington. The author has contributed to research in topics: Agrobacterium tumefaciens & Agrobacterium. The author has an hindex of 63, co-authored 185 publications receiving 16140 citations. Previous affiliations of Milton P. Gordon include Cornell University & Memorial University of Newfoundland.
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Journal ArticleDOI
Stable incorporation of plasmid DNA into higher plant cells: the molecular basis of crown gall tumorigenesis
Mary-Dell Chilton,Martin H. Drummond,Donald J. Merlo,Daniela Sciaky,Alice L. Montoya,Milton P. Gordon,Eugene W. Nester +6 more
TL;DR: It is presented that crown gall tumors are caused by the incorporation of part of a virulence plasmid carried by the inciting bacterium, Agrobacterium tumefaciens, and the relationship between this plant tumor and virally induced animal tumor systems is discussed.
Journal ArticleDOI
The Genome of the Natural Genetic Engineer Agrobacterium tumefaciens C58
Derek W. Wood,João C. Setubal,Rajinder Kaul,Dave E. Monks,João Paulo Kitajima,Vagner K. Okura,Yang Zhou,Lishan Chen,Gwendolyn E. Wood,Nalvo F. Almeida,Lisa Woo,Yuching Chen,Ian T. Paulsen,Jonathan A. Eisen,Peter D. Karp,Donald Bovee,Peter Chapman,James B. Clendenning,Glenda Deatherage,Will Gillet,Charles E. Grant,Tatyana Kutyavin,Ruth Levy,Meng-Jin Li,Erin K. McClelland,Anthony Palmieri,Christopher K. Raymond,Gregory Rouse,Channakhone Saenphimmachak,Zaining Wu,Pedro Romero,David E. Gordon,Shiping Zhang,Heayun Yoo,Yumin Tao,Phyllis Biddle,Mark Timothy Jung,William Krespan,Michael Perry,Bill Gordon-Kamm,Li Liao,Sun Kim,Carol A. Hendrick,Zuo-Yu Zhao,Maureen Dolan,Forrest Chumley,Scott V. Tingey,Jean-Francois Tomb,Milton P. Gordon,Maynard V. Olson,Eugene W. Nester +50 more
TL;DR: The 5.67-megabase genome of the plant pathogen Agrobacterium tumefaciens C58 consists of a circular chromosome, a linear chromosome, and two plasmids that suggest a recent evolutionary divergence.
Journal ArticleDOI
Plasmid required for virulence of Agrobacterium tumefaciens.
TL;DR: Findings establish unequivocally that the large plasmid determines virulence in Agrobacterium tumefaciens strain C-58.
Journal ArticleDOI
Agrobacterium tumefaciens DNA and PS8 bacteriophage DNA not detected in crown gall tumors
Mary-Dell Chilton,Thomas C. Currier,Stephen K. Farrand,Arnold J. Bendich,Milton P. Gordon,Eugene W. Nester +5 more
TL;DR: Renaturation kinetics of labeled Agrobacterium tumefaciens DNA are not influenced by addition of 10(4)-fold excess of crown gall tumor DNA, and PS8 bacteriophage DNA is not detected in crownGall tumor DNA under conditions that allow detection of 0.0007-0.001% added phage DNA.
Journal ArticleDOI
Genetic analysis of crown gall: Fine structure map of the T-DNA by site-directed mutagenesis
David J. Garfinkel,Robert B. Simpson,Lloyd W. Ream,Frank F. White,Milton P. Gordon,Eugene W. Nester +5 more
TL;DR: The map location of tumor-derived RNA transcribed from the T-DNA, the role of phytohormones in crown gall tumorigenesis and the eventual use of the Ti plasmid as a vehicle for introducing genes of choice into the genomes of higher plants are discussed.