M
Mriganka Sur
Researcher at Picower Institute for Learning and Memory
Publications - 331
Citations - 30456
Mriganka Sur is an academic researcher from Picower Institute for Learning and Memory. The author has contributed to research in topics: Visual cortex & Lateral geniculate nucleus. The author has an hindex of 88, co-authored 323 publications receiving 27646 citations. Previous affiliations of Mriganka Sur include Vanderbilt University & Massachusetts Institute of Technology.
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Journal ArticleDOI
Topographic reorganization of somatosensory cortical areas 3b and 1 in adult monkeys following restricted deafferentation
TL;DR: This paper found that after the median nerve was transected and ligated in adult owl and squirrel monkeys, the cortical sectors representing it within skin surface representations in Areas 3b and 1 were completely occupied by 'new' and expanded representations of surrounding skin fields.
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An emergent model of orientation selectivity in cat visual cortical simple cells
TL;DR: A 1:4 scale model of a 1700 microns by 200 microms region of layer IV of cat primary visual cortex is presented to demonstrate that local intracortical excitation may provide the dominant source of orientation-selective input and provide a unified account of intracellular and extracellular inhibitory blockade experiments that had previously appeared to conflict over the role of inhibition.
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Harnessing neuroplasticity for clinical applications
Steven C. Cramer,Mriganka Sur,Bruce H. Dobkin,Charles J O'Brien,Terence D. Sanger,John Q. Trojanowski,Judith M. Rumsey,Ramona Hicks,Judy L. Cameron,Daofen Chen,Wen G. Chen,Leonardo G. Cohen,Christopher deCharms,Charles J. Duffy,Guinevere F. Eden,Eberhard E. Fetz,Rosemarie Filart,Michelle Freund,Steven J. Grant,Suzanne N. Haber,Peter W. Kalivas,Bryan Kolb,Arthur F. Kramer,Minda Lynch,Helen S. Mayberg,Patrick S. McQuillen,Ralph Nitkin,Alvaro Pascual-Leone,Patricia A. Reuter-Lorenz,Nicholas D. Schiff,Anu Sharma,Lana Shekim,Michael P. Stryker,Edith V. Sullivan,Sophia Vinogradov +34 more
TL;DR: Integration of information across disciplines should enhance opportunities for the translation of neuroplasticity and circuit retraining research into effective clinical therapies.
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In vivo interrogation of gene function in the mammalian brain using CRISPR-Cas9
Lukasz Swiech,Matthias Heidenreich,Abhishek Banerjee,Naomi Habib,Yinqing Li,John J. Trombetta,Mriganka Sur,Feng Zhang +7 more
TL;DR: In this paper, an adeno-associated viral (AAV)-associated endonuclease (Cas)9 was used to edit single or multiple genes in replicating eukaryotic cells, resulting in frame-shifting insertion/deletion (indel) mutations and subsequent protein depletion.
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PROGRESSION OF CHANGE FOLLOWING MEDIAN NERVE SECTION IN THE CORTICAL REPRESENTATION OF THE HAND IN AREAS 3b AND 1 IN ADULT OWL AND SQUIRREL MONKEYS
TL;DR: The results of studies directed toward determining the time course and likely mechanisms underlying this remarkable plasticity of the cortex representing the skin of the median nerve within parietal somatosensory fields 3b and 1 are described.