Mriganka Sur

TL;DR: This paper found that after the median nerve was transected and ligated in adult owl and squirrel monkeys, the cortical sectors representing it within skin surface representations in Areas 3b and 1 were completely occupied by 'new' and expanded representations of surrounding skin fields.

TL;DR: A 1:4 scale model of a 1700 microns by 200 microms region of layer IV of cat primary visual cortex is presented to demonstrate that local intracortical excitation may provide the dominant source of orientation-selective input and provide a unified account of intracellular and extracellular inhibitory blockade experiments that had previously appeared to conflict over the role of inhibition.

TL;DR: Integration of information across disciplines should enhance opportunities for the translation of neuroplasticity and circuit retraining research into effective clinical therapies.

TL;DR: In this paper, an adeno-associated viral (AAV)-associated endonuclease (Cas)9 was used to edit single or multiple genes in replicating eukaryotic cells, resulting in frame-shifting insertion/deletion (indel) mutations and subsequent protein depletion.

TL;DR: The results of studies directed toward determining the time course and likely mechanisms underlying this remarkable plasticity of the cortex representing the skin of the median nerve within parietal somatosensory fields 3b and 1 are described.