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Nadia Falah
Researcher at Indiana University
Publications - 8
Citations - 406
Nadia Falah is an academic researcher from Indiana University. The author has contributed to research in topics: Haematopoiesis & Progenitor cell. The author has an hindex of 6, co-authored 6 publications receiving 309 citations. Previous affiliations of Nadia Falah include Nemours Foundation & Vanderbilt University.
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Journal ArticleDOI
Enhancing Hematopoietic Stem Cell Transplantation Efficacy by Mitigating Oxygen Shock.
Charlie Mantel,Heather O'Leary,Brahmananda R. Chitteti,Xinxin Huang,Scott Cooper,Giao Hangoc,Nickolay Brustovetsky,Edward F. Srour,Man Ryul Lee,Man Ryul Lee,Steve Messina-Graham,David M. Haas,Nadia Falah,Reuben Kapur,Louis M. Pelus,Nabeel Bardeesy,Julien Fitamant,Mircea Ivan,Kye Seong Kim,Hal E. Broxmeyer +19 more
TL;DR: In this article, the extraphysiologic oxygen shock/stress (EPHOSS) phenomenon was found to decrease the recovery of long-term repopulating HSCs and increase progenitor cells.
Journal ArticleDOI
Mutations in KCNK4 that Affect Gating Cause a Recognizable Neurodevelopmental Syndrome
Christiane K. Bauer,Paolo Calligari,Francesca Clementina Radio,Viviana Caputo,Maria Lisa Dentici,Nadia Falah,Frances A. High,Francesca Pantaleoni,Sabina Barresi,Andrea Ciolfi,Simone Pizzi,Alessandro Bruselles,Richard E. Person,Sarah Richards,Megan T. Cho,Daniela J. Claps Sepulveda,S. Pro,Roberta Battini,Giuseppe Zampino,Maria Cristina Digilio,Gianfranco Bocchinfuso,Bruno Dallapiccola,Lorenzo Stella,Marco Tartaglia +23 more
TL;DR: It is reported that de novo missense mutations in KCNK4 cause a recognizable syndrome with a distinctive facial gestalt, for which the acronym FHEIG is proposed (facial dysmorphism, hypertrichosis, epilepsy, intellectual disability/developmental delay, and gingival overgrowth).
Enhancing Hematopoietic Stem Cell Transplantation Efficacy by Mitigating Oxygen Shock
Charlie Mantel,Heather O'Leary,Brahmananda R. Chitteti,Xinxin Huang,Scott Cooper,Giao Hangoc,Nickolay Brustovetsky,Edward F. Srour,Man Ryul Lee,Man Ryul Lee,Steve Messina-Graham,David M. Haas,Nadia Falah,Reuben Kapur,Louis M. Pelus,Nabeel Bardeesy,Julien Fitamant,Mircea Ivan,Kye Seong Kim,Hal E. Broxmeyer +19 more
TL;DR: It is demonstrated that brief exposure to ambient oxygen decreases recovery of long-term repopulating HSCs and increases progenitor cells, a phenomenon the authors term extraphysiologic oxygen shock/stress (EPHOSS).
Journal ArticleDOI
22q11.2q13 duplication including SOX10 causes sex-reversal and peripheral demyelinating neuropathy, central dysmyelinating leukodystrophy, Waardenburg syndrome, and Hirschsprung disease.
Nadia Falah,Jennifer E. Posey,Willa Thorson,Paul J. Benke,Mustafa Tekin,Brocha Tarshish,James R. Lupski,Tamar Harel +7 more
TL;DR: The data suggest thatSOX10 duplication can cause disorders of sex development and PCWH, supporting the hypothesis that SOX10 toxic gain of function rather than dominant negative activity underlies PCWH.
Journal ArticleDOI
Investigation of genetic risk factors for chronic adult diseases for association with preterm birth
Nadia Falah,Jude J. McElroy,Victoria Snegovskikh,Charles J. Lockwood,Errol R. Norwitz,Jeffey C. Murray,Edward Kuczynski,Ramkumar Menon,Kari Teramo,Louis J. Muglia,Thomas M. Morgan +10 more
TL;DR: More statistically significant associations than expected are observed, suggesting that chance is an unlikely explanation for one or more of the associations, and larger studies are suggested to further investigate possible HLA genetic involvement in PTB.