N
Nan Lin
Researcher at Harvard University
Publications - 1220
Citations - 65601
Nan Lin is an academic researcher from Harvard University. The author has contributed to research in topics: Medicine & Breast cancer. The author has an hindex of 105, co-authored 687 publications receiving 54545 citations. Previous affiliations of Nan Lin include University of Michigan & Fujian Medical University.
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Journal ArticleDOI
Thrombopoietin, the Mp1 ligand, is essential for full megakaryocyte development.
Kenneth Kaushansky,Virginia C. Broudy,Nan Lin,Maria J. Jorgensen,John M. McCarty,Norma E. Fox,Dorothea Zucker-Franklin,Catherine E. Lofton-Day +7 more
TL;DR: It is demonstrated that neutralizing the biological activity of Tpo eliminates MK formation in response to c-kit ligand, IL-6, and IL-11, alone and in combination, but that these reagents only partially reduceMK formation in the presence of combinations of cytokines including IL-3.
Journal ArticleDOI
The Bayesian elastic net
TL;DR: A Bayesian method to solve the elastic net model using a Gibbs sampler and shows that the Bayesian elastic net behaves comparably in prediction accuracy but performs better in variable selection.
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Broadening Eligibility Criteria to Make Clinical Trials More Representative: American Society of Clinical Oncology and Friends of Cancer Research Joint Research Statement
Edward S. Kim,Suanna S. Bruinooge,Samantha A. Roberts,Gwynn Ison,Nan Lin,Lia Gore,Thomas S. Uldrick,Stuart M. Lichtman,Nancy Roach,Julia A. Beaver,Rajeshwari Sridhara,Paul J. Hesketh,Andrea M. Denicoff,Elizabeth Garrett-Mayer,Eric J. Rubin,Pratik S. Multani,Tatiana M. Prowell,Caroline Schenkel,Marina Kozak,Jeff Allen,Ellen V. Sigal,Richard L. Schilsky +21 more
TL;DR: To maximize generalizability of results, trial enrollment criteria should strive for inclusiveness and Rationale for excluding patients should be clearly articulated and reflect expected toxicities associated with the therapy under investigation.
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Getting Ahead in Urban China
Nan Lin,Yanjie Bian +1 more
TL;DR: In this article, a representative sample of the working population in Tianjin, China, is analyzed to show that entrance into the core sectors (state agencies and enterprises), rather that the job per se, constitutes the primary goal of status attainment.
Journal ArticleDOI
Trastuzumab emtansine (T-DM1) versus lapatinib plus capecitabine in patients with HER2-positive metastatic breast cancer and central nervous system metastases: a retrospective, exploratory analysis in EMILIA
Ian E. Krop,Nan Lin,Kimberly L. Blackwell,Ellie Guardino,J. Huober,M. Lu,David Miles,Meghna Samant,Manfred Welslau,Véronique Diéras +9 more
TL;DR: In patients with treated, asymptomatic CNS metastases at baseline, T-DM1 was associated with significantly improved overall survival versus capecitabine–lapatinib and trastuzumab emtansine.