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Nan Lin
Researcher at Harvard University
Publications - 1220
Citations - 65601
Nan Lin is an academic researcher from Harvard University. The author has contributed to research in topics: Medicine & Breast cancer. The author has an hindex of 105, co-authored 687 publications receiving 54545 citations. Previous affiliations of Nan Lin include University of Michigan & Fujian Medical University.
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Reversion and non-reversion mechanisms of resistance to PARP inhibitor or platinum chemotherapy in BRCA1/2-mutant metastatic breast cancer
Adrienne G. Waks,Ofir Cohen,Ofir Cohen,Bose Kochupurakkal,Dae Hyun Kim,Dae Hyun Kim,Connor E. Dunn,Jorge Buendia Buendia,Jorge Buendia Buendia,Seth A. Wander,Karla Helvie,Max Lloyd,Max Lloyd,Lori Marini,Melissa E. Hughes,Samuel S. Freeman,S. Percy Ivy,Joseph Geradts,Steven J. Isakoff,Patricia LoRusso,Viktor A. Adalsteinsson,Sara M. Tolaney,Sara M. Tolaney,Ursula A. Matulonis,Ursula A. Matulonis,Ian E. Krop,Ian E. Krop,Alan D. D'Andrea,Eric P. Winer,Eric P. Winer,Nan Lin,Nan Lin,Geoffrey I. Shapiro,Nikhil Wagle +33 more
TL;DR: The presence of RAD51 foci by immunohistochemistry was consistent with BRCA1/2 protein functional status from genomic data and predicted response to later DNA-damaging therapy, supporting RAD51 focus formation as a clinically useful biomarker.
Journal ArticleDOI
Research studies in patterns of scientific communication: III. Information-exchange processes associated with the production of journal articles☆
TL;DR: How scientists assimilate and use information contained in these articles when this information is also disseminated via informal media prior to its appearance in journal articles is discussed.
Journal ArticleDOI
The Left Fusiform Gyrus is a Critical Region Contributing to the Core Behavioral Profile of Semantic Dementia
Junhua Ding,Keliang Chen,Yan Chen,Yuxing Fang,Qing Yang,Yingru Lv,Nan Lin,Yanchao Bi,Qihao Guo,Zaizhu Han +9 more
TL;DR: It is found that the gray matter volumes of two regions [left fusiform gyrus (lFFG) and left parahippocampal gyrus) significantly correlated with the semantic scores of patients with SD and that the lFFG could be a critical region contributing to the semantic deficits of SD.
Journal ArticleDOI
Exposure and size distribution of nitrated and oxygenated polycyclic aromatic hydrocarbons among the population using different household fuels
Guofeng Shen,Yuanchen Chen,Wei Du,Nan Lin,Xilong Wang,Hefa Cheng,Junfeng Liu,Chunyu Xue,Guangqing Liu,Eddy Y. Zeng,Baoshan Xing,Shu Tao +11 more
TL;DR: The inhalation exposure levels for residents adopting wood gasifier burners was significantly lower than the documented results for those burning wood in typical built-in brick stoves, and comparable to those using LPG and electricity, which provided vital information for clean stove development and intervention programs.
Journal ArticleDOI
STING agonism reprograms tumor-associated macrophages and overcomes resistance to PARP inhibition in BRCA1-deficient models of breast cancer
Qiwei Wang,Johann Bergholz,Liya Ding,Ziying Lin,Sheheryar Kabraji,Melissa E. Hughes,Xiadi He,Shaozhen Xie,Tao Jiang,Weihua Wang,Jason J. Zoeller,Hye-Jung Kim,Thomas M. Roberts,Panagiotis A. Konstantinopoulos,Ursula A. Matulonis,Deborah A. Dillon,Eric P. Winer,Nan Lin,Jean J. Zhao +18 more
TL;DR: In this article , a syngeneic genetically-engineered mouse model of breast tumor driven by Brca1 deficiency was used to demonstrate the importance of targeting innate immune suppression to facilitate PARPi-mediated engagement of anti-tumor immunity in breast cancer.