Nan Lin

TL;DR: In heavily pretreated HER2-positive MBC patients, prior exposure to T-DM1 does not exhaust the potential benefit of ongoing anti-HER2 therapy with trastuzumab- and/or lapatinib-based regimens.

TL;DR: Brain scans coregistered with structural magnetic resonance imaging were used to determine whether metabolic activity in the insula and hypothalamic thermoregulatory and estrogen-feedback regions measured before and in response to AET predict hot flashes, and genetic variability in CYP2D6 may underlie the neurobiological predisposition to hot flashes induced by AET.

TL;DR: The Global Breast Cancer Initiative (GBCI) as mentioned in this paper is a systematized approach, with the goal to increase the fraction of newly diagnosed invasive cancers being stage 1 or more, ensure diagnostic work-up to be completed within 60 days from the first connection with the primary healthcare providers to avoid delays in diagnosis and treatment and assure 80% or more women with breast cancer to undergo and complete multimodal treatments.

TL;DR: The Two-Step Flow of Communication (TSFC) hypothesis as discussed by the authors has been studied extensively in the literature and has been used to explain the role of interpersonal communication in the flow of ideas.

TL;DR: Tumor subtype is associated with risk of CNS progression after SRS for breast cancer brain metastases and progressive extracranial disease may be an important prognostic factor for OS.