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Nan Lin
Researcher at Harvard University
Publications - 1220
Citations - 65601
Nan Lin is an academic researcher from Harvard University. The author has contributed to research in topics: Medicine & Breast cancer. The author has an hindex of 105, co-authored 687 publications receiving 54545 citations. Previous affiliations of Nan Lin include University of Michigan & Fujian Medical University.
Papers
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Journal ArticleDOI
Transcriptomic insights into the immune response of the intestine to Aeromonas veronii infection in northern snakehead (Channa argus).
Peng Sun,Di Zhang,Nan Lin,Xiao-fei Li,Yi Ma,Hui Li,Ye Tian,Tao Wang,Shahrood Ahmed Siddiquid,Wuwen Sun,Lei Zhang,Xiaofeng Shan,Chun-Feng Wang,Ai-Dong Qian,Dongxing Zhang +14 more
TL;DR: In this article , a de novo northern snakehead (Channa argus) transcriptome assembly using Illumina sequencing platform was performed, and the results reflected the consistency of the expression levels between qRT-PCR and RNA-seq data.
Posted ContentDOI
Genomic and Transcriptomic Determinants of Resistance to CDK4/6 Inhibitors and Response to Combined Exemestane plus Everolimus and Palbociclib in Patients with Metastatic Hormone Receptor Positive Breast Cancer
Jorge Gómez Tejeda Zañudo,Romualdo Barroso-Sousa,Esha Jain,Quanxiu Jin,Jorge E. Buendia-Buendia,Alyssa Pereslete,Daniel L. Abravanel,Arlindo R. Ferreira,Eileen Wrabel,Karla Helvie,Melissa E. Hughes,Ann H. Partridge,Beth Overmoyer,Nan Lin,Nabihah Tayob,Sara M. Tolaney,N. Wagle +16 more
TL;DR: A phase I/II clinical trial of exemestane plus everolimus and palbociclib, triplet therapy for CDK4/6i-resistant hormone receptor-positive (HR+), HER2- metastatic breast cancer, revealed that genomic resistance mechanisms were associated with transcriptomic features in their respective pathways, suggesting that transcriptsomic features could be used to identify the pathways driving resistance.
Book ChapterDOI
APPENDIX C – Research Studies in Patterns of Scientific Communication: I, General Description of Research Program
TL;DR: In this paper, the authors describe the general procedures and some findings of over 70 studies which they conducted from 1966 to 1971 on the information exchange activities of over 12,000 scientists and engineers in a sample of nine physical, social and engineering sciences.
Journal ArticleDOI
Whole exome sequencing reveals novel variants associated with diminished ovarian reserve in young women
Nan Lin,Wanxue Xu,Huimin Liu,Rui Zhou,Si-Ping Zou,Shiqing Wang,Si-Cong Li,Ze Hua Yang,Yongjun Piao,Yunshan Zhang +9 more
TL;DR: In this article , a set of mutated genes that may be related to DOR was obtained, where the missense variant on GPR84 was selected for further study, and it was found that GPR 84Y370H variant promotes the expression of proinflammatory cytokines (TNF-α, IL12B, IL-1β) and chemokines (CCL2, CCL5), as well as activation of NF-κB signaling pathway.
Proceedings ArticleDOI
Research on multi-subject transaction optimization of integrated energy system based on coordinated operation
TL;DR: In this article , a preferential method for cooperative alliance of integrated energy system based on the solution idea of cooperative game kernel as the theoretical basis and operation optimization method as technical support is proposed.