Nora F. Dengler

TL;DR: Consensus recommendations for electrocorticographic methods to record, classify, and score spreading depolarizations and associated spreading depressions are provided, which offer distinct advantages over other neuromonitoring modalities and allow for future refinement through less invasive and more automated approaches.

TL;DR: Analysis of simultaneous electrocorticography and tissue partial pressure of oxygen recording in 33 aneurysmal subarachnoid hemorrhage patients supports that long spreading depolarization-induced periods of isoelectricity are useful to detect energy compromise remotely, which is valuable because the exact location of future developing pathology is unknown at the time when the neurosurgeon implants recording devices.

TL;DR: The newly developed SDASH score is a reliable tool for predicting shunt-dependent hydrocephalus (SDHC) after aneurysmal subarachnoid hemorrhage (aSAH) and is more intuitive than existing scores that were shown to predict SDHC.

TL;DR: Radiographic, clinical and combined grading systems in aneurysmal subarachnoid hemorrhage are compared to improve the comparability of grading scales and predict outcome.

TL;DR: One key finding was that spreading depolarization-variables were included in every multiple regression model of early, delayed and total brain damage, patient outcome and death, strongly suggesting that they are an independent biomarker of progressive brain injury.