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Sergei A. Kirov
Researcher at Georgia Regents University
Publications - 48
Citations - 3776
Sergei A. Kirov is an academic researcher from Georgia Regents University. The author has contributed to research in topics: Cortical spreading depression & Dendritic spine. The author has an hindex of 28, co-authored 41 publications receiving 3244 citations. Previous affiliations of Sergei A. Kirov include Discovery Institute & Harvard University.
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Journal ArticleDOI
Slices have more synapses than perfusion-fixed hippocampus from both young and mature rats
TL;DR: It is suggested that spines form in response to the loss of synaptic activity when slices are removed from the rest of the brain and during the subsequent 1 hr recovery period, which is the longest time investigated.
Journal ArticleDOI
The continuum of spreading depolarizations in acute cortical lesion development: Examining Leão's legacy
Jed A. Hartings,C. William Shuttleworth,Sergei A. Kirov,Cenk Ayata,Jason M. Hinzman,Brandon Foreman,R. David Andrew,Martyn G. Boutelle,Kevin C. Brennan,Andrew P. Carlson,Markus Dahlem,Christoph Drenckhahn,Christian Dohmen,Martin Fabricius,Eszter Farkas,Delphine Feuerstein,Rudolf Graf,Raimund Helbok,Martin Lauritzen,Sebastian Major,Ana I Oliveira-Ferreira,Frank Richter,Eric Rosenthal,Oliver W. Sakowitz,Renán Sánchez-Porras,Edgar Santos,Michael Schöll,Anthony J. Strong,Anja Urbach,M. Brandon Westover,Maren K.L. Winkler,Otto W. Witte,Johannes Woitzik,Jens P. Dreier +33 more
TL;DR: The spreading depolarization continuum further applies to other models of acute cortical lesions, suggesting that it is a universal principle of cortical lesion development.
Journal ArticleDOI
Plasticity of perisynaptic astroglia during synaptogenesis in the mature rat hippocampus.
TL;DR: It is suggested that as synapses enlarge and release more neurotransmitter, they attract astroglial processes to a discrete portion of their perimeters, further enhancing synaptic efficacy without limiting the potential for cross talk with neighboring synapses in the mature rat hippocampus.
Journal ArticleDOI
Recording, analysis, and interpretation of spreading depolarizations in neurointensive care: Review and recommendations of the COSBID research group
Jens P. Dreier,Martin Fabricius,Cenk Ayata,Oliver W. Sakowitz,C. William Shuttleworth,Christian Dohmen,Christian Dohmen,Rudolf Graf,Peter Vajkoczy,Raimund Helbok,Michiyasu Suzuki,Alois Josef Schiefecker,Sebastian Major,Maren K.L. Winkler,Eun Jeung Kang,Denny Milakara,Ana I Oliveira-Ferreira,Clemens Reiffurth,Gajanan S. Revankar,Kazutaka Sugimoto,Nora F. Dengler,Nils Hecht,Brandon Foreman,Bart Feyen,Daniel Kondziella,Christian K. Friberg,Henning Piilgaard,Eric Rosenthal,M. Brandon Westover,Anna Maslarova,Edgar Santos,Daniel N. Hertle,Renán Sánchez-Porras,Sharon L. Jewell,Baptiste Balança,Baptiste Balança,Johannes Platz,Jason M. Hinzman,Janos Luckl,Karl Schoknecht,Michael Schöll,Christoph Drenckhahn,Delphine Feuerstein,Nina Eriksen,Viktor Horst,Julia S. Bretz,Paul Jahnke,Michael Scheel,Georg Bohner,Egill Rostrup,Bente Pakkenberg,Uwe Heinemann,Jan Claassen,Andrew P. Carlson,Christina M. Kowoll,Christina M. Kowoll,Svetlana Lublinsky,Yoash Chassidim,Ilan Shelef,Alon Friedman,Gerrit Brinker,Michael Reiner,Sergei A. Kirov,R. David Andrew,Eszter Farkas,Erdem Güresir,Hartmut Vatter,Lee S Chung,Kc Brennan,Thomas Lieutaud,Thomas Lieutaud,Stéphane Marinesco,Andrew I R Maas,Juan Sahuquillo,Markus Dahlem,Frank Richter,Oscar Herreras,Martyn G. Boutelle,David O. Okonkwo,M. Ross Bullock,Otto W. Witte,Peter Martus,Arn M. J. M. van den Maagdenberg,Michel D. Ferrari,Rick M. Dijkhuizen,Lori Shutter,Norberto Andaluz,André P. Schulte,Brian A. MacVicar,Tomas Watanabe,Johannes Woitzik,Martin Lauritzen,Anthony J. Strong,Jed A. Hartings +93 more
TL;DR: Consensus recommendations for electrocorticographic methods to record, classify, and score spreading depolarizations and associated spreading depressions are provided, which offer distinct advantages over other neuromonitoring modalities and allow for future refinement through less invasive and more automated approaches.
Journal ArticleDOI
Real-time passive volume responses of astrocytes to acute osmotic and ischemic stress in cortical slices and in vivo revealed by two-photon microscopy.
TL;DR: In vivo, rapid astroglial swelling was confirmed within 6 min following intraperitoneal water injection or during the 6–12 min following cardiac arrest, and astrocytes better recover from brief ischemic insult in cortical slices, probably because their aquaporins facilitate water efflux.