Oliver Hofmann

TL;DR: Repeated, low-dose LPS inhalation resulted in airway hyperresponsiveness, associated with a failure to resolve the proinflammatory response, an inverted macrophage to DC ratio, and a significant rise in the inflammatory DC population.

TL;DR: It is demonstrated that the non-diseased male urinary proteome is quantitatively affected by age, has age-specific subproteomes, and identifies a common sub Proteome with no age-dependent abundance variations.

TL;DR: bcbioRNASeq, a Bioconductor package that provides ready-to-render templates, objects and wrapper functions to post-process bcbio RNA sequencing output data, helps automate the generation of high-level RNA-seq reports, facilitating the quality control analyses, identification of differentially expressed genes and functional enrichment analyses.

TL;DR: This approach provides a robust platform for large-scale phosphoproteomic analyses performed with limited numbers of rare progenitor cells and comprises a new resource for understanding the molecular signaling networks that underlie hematopoietic stem cell mobilization.

TL;DR: In this paper, the Gower II hemoglobin tetramer was solved by molecular replacement and refined at 2.9 A to give a final model with R -factor=0.185 and R free =0.235.