Z
Z. Kutalik
Researcher at University of Lausanne
Publications - 21
Citations - 3404
Z. Kutalik is an academic researcher from University of Lausanne. The author has contributed to research in topics: Genome-wide association study & Population. The author has an hindex of 12, co-authored 21 publications receiving 3118 citations. Previous affiliations of Z. Kutalik include Swiss Institute of Bioinformatics & University of Turku.
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Journal ArticleDOI
Modulation of genetic associations with serum urate levels by body-mass-index in humans
Jennifer E. Huffman,Eva Albrecht,Alexander Teumer,Massimo Mangino,Karen Kapur,Toby Johnson,Z. Kutalik,Nicola Pirastu,Giorgio Pistis,Lorna M. Lopez,Toomas Haller,Perttu Salo,Anuj Goel,Man Li,Toshiko Tanaka,Abbas Dehghan,Daniela Ruggiero,Giovanni Malerba,Albert V. Smith,Ilja M. Nolte,Laura Portas,Amanda Phipps-Green,Lora Boteva,Pau Navarro,Åsa Johansson,Andrew A. Hicks,Ozren Polasek,Tõnu Esko,John F. Peden,Sarah E. Harris,Federico Murgia,Sarah H. Wild,Albert Tenesa,Adrienne Tin,Evelin Mihailov,Anne Grotevendt,Gauti Kjartan Gislason,Josef Coresh,Pio D'Adamo,Sheila Ulivi,Peter Vollenweider,Gérard Waeber,Susan Campbell,Ivana Kolcic,Krista Fisher,Margus Viigimaa,Jeffrey Metter,Corrado Masciullo,Elisabetta Trabetti,Cristina Bombieri,Rossella Sorice,Angela Doering,Eva Reischl,Konstantin Strauch,Albert Hofman,André G. Uitterlinden,Melanie Waldenberger,H-Erich Wichmann,Gail Davies,Alan J. Gow,Nicola Dalbeth,Lisa K. Stamp,Johannes H. Smit,Mirna Kirin,Ramaiah Nagaraja,Matthias Nauck,Claudia Schurmann,Kathrin Budde,Susan M. Farrington,Evropi Theodoratou,Antti Jula,Veikko Salomaa,Cinzia Sala,Christian Hengstenberg,Michel Burnier,R Maegi,Norman Klopp,Stefan Kloiber,Sabine Schipf,Samuli Ripatti,Stefano Cabras,Nicole Soranzo,Georg Homuth,Teresa Nutile,Patricia B. Munroe,Nicholas D. Hastie,Harry Campbell,Igor Rudan,Claudia P. Cabrera,Chris Haley,Oscar H. Franco,Tony R. Merriman,Vilmundur Gudnason,Mario Pirastu,Brenda W.J.H. Penninx,Brenda W.J.H. Penninx,Harold Snieder,Andres Metspalu,Marina Ciullo,Peter P. Pramstaller,Cornelia M. van Duijn,Luigi Ferrucci,Giovanni Gambaro,Ian J. Deary,Malcolm G. Dunlop,James F. Wilson,Paolo Gasparini,Ulf Gyllensten,Tim D. Spector,Alan F. Wright,Caroline Hayward,Hugh Watkins,Markus Perola,Murielle Bochud,W. H. Linda Kao,Mark J. Caulfield,Daniela Toniolo,Henry Voelzke,Christian Gieger,Anna Koettgen,Veronique Vitart +120 more
TL;DR: Interactions between body mass index (BMI) and common genetic variants affecting serum urate levels, genome-wide, and regression-type analyses in a non BMI-stratified overall sample suggested a role for N-glycan biosynthesis as a prominent urate-associated pathway in the lean stratum.
Posted ContentDOI
Unraveling the polygenic architecture of complex traits using blood eQTL metaanalysis
Urmo Võsa,Annique Claringbould,Harm-Jan Westra,Marc Jan Bonder,Patrick Deelen,Biao Zeng,Holger Kirsten,Ashis Saha,Roman Kreuzhuber,Silva Kasela,Natalia Pervjakova,Alvaes I,Marie-Julie Favé,Mawusse Agbessi,Mark W. Christiansen,Rick Jansen,Ilkka Seppälä,Lin Tong,Alexander Teumer,Katharina Schramm,Gibran Hemani,Joost Verlouw,Hanieh Yaghootkar,Reyhan Sonmez,Andrew A. Brown,Andrew A. Brown,Kukushkina,Anette Kalnapenkis,Sina Rüeger,Eleonora Porcu,Jaanika Kronberg-Guzman,Jarno Kettunen,Joseph E. Powell,Bernett Lee,Futao Zhang,Wibowo Arindrarto,Frank Beutner,Harm Brugge,Dmitreva J,Mahmoud Elansary,Benjamin P. Fairfax,Michel Georges,Bastiaan T. Heijmans,Mika Kähönen,Yungil Kim,Julian C. Knight,Peter Kovacs,Knut Krohn,Shuang Li,Markus Loeffler,Urko M. Marigorta,Hailiang Mei,Yukihide Momozawa,Martina Müller-Nurasyid,Matthias Nauck,Michel G. Nivard,Brenda W.J.H. Penninx,Jonathan K. Pritchard,Olli T. Raitakari,Rotzchke O,Eline Slagboom,Coen D.A. Stehouwer,Michael Stumvoll,Patrick F. Sullivan,Peter A C 't Hoen,Joachim Thiery,Anke Tönjes,van Dongen J,van Iterson M,Jan H. Veldink,Uwe Völker,C Wijmenga,Morris A. Swertz,Anand Kumar Andiappan,Grant W. Montgomery,Samuli Ripatti,Markus Perola,Z. Kutalik,Emmanouil T. Dermitzakis,Sven Bergmann,Timothy M. Frayling,van Meurs J,Holger Prokisch,Habibul Ahsan,Brandon L. Pierce,Terho Lehtimäki,D.I. Boomsma,Bruce M. Psaty,Sina A. Gharib,Philip Awadalla,Lili Milani,Willem H. Ouwehand,Kate Downes,Oliver Stegle,Alexis Battle,Jian Yang,Peter M. Visscher,Markus Scholz,Greg Gibson,Tõnu Esko,Lude Franke +100 more
TL;DR: It is observed that cis-eQTLs can be detected for 88% of the studied genes, but that they have a different genetic architecture compared to disease-associated variants, limiting the ability to use cis- eZTLs to pinpoint causal genes within susceptibility loci.
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture
Sonja I. Berndt,Stefan Gustafsson,Reedik Maegi,Andrea Ganna,Eleanor Wheeler,Mary F. Feitosa,Anne E. Justice,Keri L. Monda,Damien C. Croteau-Chonka,Felix R. Day,Tõnu Esko,Tove Fall,Teresa Ferreira,Davide Gentilini,Anne U. Jackson,Jian'an Luan,Joshua C. Randall,Sailaja Vedantam,Cristen J. Willer,Thomas W. Winkler,Andrew R. Wood,Tsegaselassie Workalemahu,Yi-Juan Hu,Sang Hong Lee,Liming Liang,Danyu Lin,Josine L. Min,Benjamin M. Neale,Gudmar Thorleifsson,Jian Yang,Eva Albrecht,Najaf Amin,Jennifer L. Bragg-Gresham,Gemma Cadby,Martin den Heijer,Niina Eklund,Krista Fischer,Anuj Goel,Jouke-Jan Hottenga,Jennifer E. Huffman,Ivonne Jarick,Åsa Johansson,Toby Johnson,Stavroula Kanoni,Marcus E. Kleber,Inke R. Koenig,Kati Kristiansson,Z. Kutalik,Claudia Lamina,Cécile Lecoeur,Guo Li,Massimo Mangino,Wendy L. McArdle,Carolina Medina-Gomez,Martina Mueller-Nurasyid,Julius S. Ngwa,Ilja M. Nolte,Lavinia Paternoster,Sonali Pechlivanis,Markus Perola,Marjolein Peters,Michael Preuss,Lynda M. Rose,Jianxin Shi,Dmitry Shungin,Albert V. Smith,Rona J. Strawbridge,Ida Surakka,Alexander Teumer,Mieke D. Trip,Jonathan Tyrer,Jana V. van Vliet-Ostaptchouk,Liesbeth Vandenput,Lindsay L. Waite,Jing Hua Zhao,Devin Absher,Folkert W. Asselbergs,Mustafa Atalay,Antony P. Attwood,Anthony J. Balmforth,Hanneke Basart,John Beilby,Lori L. Bonnycastle,Paolo Brambilla,Marcel Bruinenberg,Harry Campbell,Daniel I. Chasman,Peter S. Chines,Francis S. Collins,John M. C. Connell,William O.C.M. Cookson,Ulf de Faire,Femmie de Vegt,Mariano Dei,Maria Dimitriou,Sarah Edkins,Karol Estrada,David M. Evans,Martin Farrall,Marco M Ferrario,Jean Ferrières,Lude Franke,Francesca Frau,Pablo V. Gejman,Harald Grallert,Henrik Groenberg,Vilmundur Gudnason,Alistair S. Hall,Per Hall,Anna-Liisa Hartikainen,Caroline Hayward,Nancy L. Heard-Costa,Andrew Heath,Johannes Hebebrand,Georg Homuth,Frank B. Hu,Sarah E. Hunt,Elina Hyppoenen,Carlos Iribarren,Kevin B. Jacobs,John-Olov Jansson,Antti Jula,Mika Kähönen,Sekar Kathiresan,Frank Kee,Kay-Tee Khaw,Mika Kivimäki,Wolfgang Koenig,Aldi T. Kraja,Meena Kumari,Kari Kuulasmaa,Johanna Kuusisto,Jaana Laitinen,Timo A. Lakka,Claudia Langenberg,Lenore J. Launer,Lars Lind,Jaana Lindström,Jianjun Liu,Antonio Liuzzi,Marja-Liisa Lokki,Mattias Lorentzon,Pamela A. F. Madden,Patrik K. E. Magnusson,Paolo Manunta,Diana Marek,Winfried Maerz,Irene Mateo Leach,Barbara McKnight,Sarah E. Medland,Evelin Mihailov,Lili Milani,Grant W. Montgomery,Vincent Mooser,Thomas W. Muehleisen,Patricia B. Munroe,Arthur W. Musk,Narisu Narisu,Gerjan Navis,George Nicholson,Ellen A. Nohr,Ken K. Ong,Ben A. Oostra,Colin N. A. Palmer,Aarno Palotie,John F. Peden,Nancy L. Pedersen,Annette Peters,Ozren Polasek,Anneli Pouta,Peter P. Pramstaller,Inga Prokopenko,Carolin Puetter,Aparna Radhakrishnan,Olli T. Raitakari,Augusto Rendon,Fernando Rivadeneira,Igor Rudan,Timo Saaristo,Jennifer G. Sambrook,Alan R. Sanders,Serena Sanna,Jouko Saramies,Sabine Schipf,Stefan Schreiber,Heribert Schunkert,So-Youn Shin,Stefano Signorini,Juha Sinisalo,Boris Skrobek,Nicole Soranzo,Alena Stančáková,Klaus Stark,Jonathan Stephens,Kathleen Stirrups,Ronald P. Stolk,Michael Stumvoll,Amy J. Swift,Eirini V. Theodoraki,Barbara Thorand,David-Alexandre Trégouët,Elena Tremoli,Melanie M. van der Klauw,Joyce B. J. van Meurs,Sita H. Vermeulen,Jorma Viikari,Jarmo Virtamo,Veronique Vitart,Gérard Waeber,Zhaoming Wang,Elisabeth Widen,Sarah H. Wild,Gonneke Willemsen,Bernhard R. Winkelmann,Jacqueline C.M. Witteman,Bruce H. R. Wolffenbuttel,Andrew Wong,Alan F. Wright,M. Carola Zillikens,Philippe Amouyel,Bernhard O. Boehm,Eric Boerwinkle,Dorret I. Boomsma,Mark J. Caulfield,Stephen J. Chanock,L. Adrienne Cupples,Daniele Cusi,George Dedoussis,Jeanette Erdmann,Johan G. Eriksson,Paul W. Franks,Philippe Froguel,Christian Gieger,Ulf Gyllensten,Anders Hamsten,Tamara B. Harris,Christian Hengstenberg,Andrew A. Hicks,Aroon D. Hingorani,Anke Hinney,Albert Hofman,Kees Hovingh,Kristian Hveem,Thomas Illig,Marjo-Riitta Järvelin,Karl-Heinz Joeckel,Sirkka Keinänen-Kiukaanniemi,Lambertus A. Kiemeney,Diana Kuh,Markku Laakso,Terho Lehtimäki,Douglas F. Levinson,Nicholas G. Martin,Andres Metspalu,Andrew D. Morris,Markku S. Nieminen,Inger Njølstad,Claes Ohlsson,Albertine J. Oldehinkel,Willem H. Ouwehand,Lyle J. Palmer,Brenda W.J.H. Penninx,Chris Power,Michael A. Province,Bruce M. Psaty,Lu Qi,Rainer Rauramaa,Paul M. Ridker,Samuli Ripatti,Veikko Salomaa,Nilesh J. Samani,Harold Snieder,Thorkild I. A. Sørensen,Tim D. Spector,Kari Stefansson,Anke Tönjes,Jaakko Tuomilehto,André G. Uitterlinden,Matti Uusitupa,Pim van der Harst,Peter Vollenweider,Henri Wallaschofski,Nicholas J. Wareham,Hugh Watkins,H-Erich Wichmann,James F. Wilson,Gonçalo R. Abecasis,Themistocles L. Assimes,Inês Barroso,Michael Boehnke,Ingrid B. Borecki,Panos Deloukas,Caroline S. Fox,Timothy M. Frayling,Leif Groop,Talin Haritunian,Iris M. Heid,David J. Hunter,Robert C. Kaplan,Fredrik Karpe,Miriam F. Moffatt,Karen L. Mohlke,Jeffrey R. O'Connell,Yudi Pawitan,Eric E. Schadt,David Schlessinger,Valgerdur Steinthorsdottir,David P. Strachan,Unnur Thorsteinsdottir,Cornelia M. van Duijn,Peter M. Visscher,Anna Maria Di Blasio,Joel N. Hirschhorn,Cecilia M. Lindgren,Andrew P. Morris,David Meyre,Andr Scherag,Mark I. McCarthy,Elizabeth K. Speliotes,Kari E. North,Ruth J. F. Loos,Erik Ingelsson +321 more
Journal ArticleDOI
Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways
Lisette Stolk,John R. B. Perry,John R. B. Perry,Daniel I. Chasman,Chunyan He,Massimo Mangino,Patrick Sulem,Maja Barbalić,Linda Broer,Enda M. Byrne,Florian Ernst,Tmu Esko,Nora Franceschini,Daniel F. Gudbjartsson,Jouke-Jan Hottenga,Peter Kraft,Peter Kraft,Patrick F. McArdle,Eleonora Porcu,So-Youn Shin,Albert V. Smith,Sophie H. Van Wingerden,Guangju Zhai,Guangju Zhai,Wei V. Zhuang,Eva Albrecht,Behrooz Z. Alizadeh,Thor Aspelund,Stefania Bandinelli,Lovorka Barać Lauc,Jacques S. Beckmann,Mladen Boban,Eric Boerwinkle,Frank J.M. Broekmans,Andrea Burri,Harry Campbell,Stephen J. Chanock,Constance Chen,Marilyn C. Cornelis,Tanguy Corre,Andrea D. Coviello,Pio D'Adamo,Gail Davies,Ulf de Faire,Eco J. C. de Geus,Ian J. Deary,George Dedoussis,Panagiotis Deloukas,Shah Ebrahim,Gudny Eiriksdottir,Valur Emilsson,Johan G. Eriksson,Bart C.J.M. Fauser,Liana Ferreli,Luigi Ferrucci,Krista Fischer,Aaron R. Folsom,Melissa E. Garcia,Paolo Gasparini,Christian Gieger,Nicole L. Glazer,Diederick E. Grobbee,Per Hall,Toomas Haller,Susan E. Hankinson,Merli Hass,Caroline Hayward,Andrew C. Heath,Albert Hofman,Erik Ingelsson,A. Cecile J.W. Janssens,Andrew D. Johnson,David Karasik,David Karasik,Sharon L.R. Kardia,Jules J. Keyzer,Douglas P. Kiel,Douglas P. Kiel,Ivana Kolcic,Z. Kutalik,Z. Kutalik,Jari Lahti,Sandra Lai,Triin Laisk,Joop S.E. Laven,Debbie A Lawlor,Jianjun Liu,Lorna M. Lopez,Yvonne V. Louwers,Patrik K. E. Magnusson,Mara Marongiu,Nicholas G. Martin,Irena Martinović Klarić,Corrado Masciullo,Barbara McKnight,Sarah E. Medland,David Melzer,Vincent Mooser,Pau Navarro,Anne B. Newman,Dale R. Nyholt,N. Charlotte Onland-Moret,Aarno Palotie,Guillaume Paré,Guillaume Paré,Alexander N. Parker,Nancy L. Pedersen,Petra H.M. Peeters,Giorgio Pistis,Andrew S. Plump,Ozren Polasek,Victor J M Pop,Bruce M. Psaty,Bruce M. Psaty,Katri R Currency Signikkönen,Emil Rehnberg,Jerome I. Rotter,Igor Rudan,Igor Rudan,Cinzia Sala,Andres Salumets,Angelo Scuteri,Andrew B. Singleton,Jennifer A. Smith,Harold Snieder,Nicole Soranzo,Nicole Soranzo,Simon N. Stacey,John M. Starr,Maria G. Stathopoulou,Kathleen Stirrups,Ronald P. Stolk,Unnur Styrkarsdottir,Yan V. Sun,Albert Tenesa,Barbara Thorand,Daniela Toniolo,Laufey Tryggvadottir,Kim Tsui,Sheila Ulivi,Rob M. van Dam,Rob M. van Dam,Yvonne T. van der Schouw,Carla H. van Gils,Peter Van Nierop,Jacqueline M. Vink,Peter M. Visscher,Peter M. Visscher,Marlies Voorhuis,Gérard Waeber,Henri Wallaschofski,H.-Erich Wichmann,Elisabeth Widen,Colette J M Wijnands-van Gent,Gonneke Willemsen,James F. Wilson,Bruce H. R. Wolffenbuttel,Alan F. Wright,Laura M. Yerges-Armstrong,Tatijana Zemunik,Lina Zgaga,Lina Zgaga,M. Carola Zillikens,Marek Zygmunt,Alice M. Arnold,Dorret I. Boomsma,Julie E. Buring,Laura Crisponi,Ellen W. Demerath,Ellen W. Demerath,Vilmundur Gudnason,Tamara B. Harris,Frank B. Hu,David J. Hunter,David J. Hunter,Lenore J. Launer,Andres Metspalu,Grant W. Montgomery,Ben A. Oostra,Paul M. Ridker,Serena Sanna,David Schlessinger,Tim D. Spector,Kari Stefansson,Kari Stefansson,Elizabeth A. Streeten,Unnur Thorsteinsdottir,Unnur Thorsteinsdottir,Manuela Uda,André G. Uitterlinden,Cornelia M. van Duijn,Henry Völzke,Anna Murray,Anna Murray,Joanne M. Murabito,Jenny A. Visser,Jenny A. Visser,Kathryn L. Lunetta,Kathryn L. Lunetta +198 more
TL;DR: A meta-analysis of 22 genome-wide association studies in 38,968 women of European descent identified 13 loci newly associated with age at natural menopause, including genes implicated in DNA repair, immune function and immune function.
Journal ArticleDOI
Meta-analysis identifies multiple loci associated with kidney function–related traits in east Asian populations
Yukinori Okada,Xueling Sim,Xueling Sim,Min Jin Go,Jer-Yuarn Wu,Jer-Yuarn Wu,Dongfeng Gu,Fumihiko Takeuchi,Atsushi Takahashi,Shiro Maeda,Tatsuhiko Tsunoda,Peng Chen,Su Chi Lim,Su Chi Lim,Tien Yin Wong,Tien Yin Wong,Tien Yin Wong,Jianjun Liu,Terri L. Young,Tin Aung,Tin Aung,Mark Seielstad,Yik Ying Teo,Yik Ying Teo,Young-Jin Kim,Jong-Young Lee,Bok Ghee Han,Daehee Kang,Chien Hsiun Chen,Chien Hsiun Chen,Fuu Jen Tsai,Li-Ching Chang,S. J. Fann,Hao Mei,Dabeeru C. Rao,James E. Hixson,Shufeng Chen,Tomohiro Katsuya,Motohide Isono,Toshio Ogihara,Toshio Ogihara,John C. Chambers,Weihua Zhang,Jaspal S. Kooner,E Albrecht,Kazuhiko Yamamoto,Michiaki Kubo,Yusuke Nakamura,Kamatani Naoyuki,Norihiro Kato,Jiang He,Yuan-Tsong Chen,Yoon Shin Cho,E-Shyong Tai,Toshihiro Tanaka,Graham M. Lord,P. van der Harst,Debbie A Lawlor,Jobanpreet Sehmi,Daniel P. Gale,Mark N. Wass,Kourosh R. Ahmadi,Stephan J. L. Bakker,Jacqui Beckmann,Hjg Bilo,Murielle Bochud,Morris J. Brown,M. J. Caulfield,Jmc Connell,H.T. Cook,Ioana Cotlarciuc,George Davey Smith,R. de Silva,G. Deng,Olivier Devuyst,L. D. Dikkeschei,N. Dimkovic,M. Dockrell,Anna F. Dominiczak,S Ebrahim,Thomas Eggermann,Martin Farrall,L Ferrucci,Juergen Floege,Nita G. Forouhi,Ron T. Gansevoort,X. Han,Bo Hedblad,J. J. van der Heide,Bouke G. Hepkema,Maria P. Hernandez-Fuentes,Elina Hyppönen,Toby Johnson,P. E. De Jong,Nanno Kleefstra,Vasiliki Lagou,Marta Lapsley,Yun Li,Ruth J. F. Loos,Jian'an Luan,Karin Luttropp,Céline Maréchal,Olle Melander,Patricia B. Munroe,Louise Nordfors,Afshin Parsa,Leena Peltonen,B.W.J.H. Penninx,Esperanza Perucha,A Pouta,Inga Prokopenko,Paul Roderick,Aimo Ruokonen,Nilesh J. Samani,Serena Sanna,Martin Schalling,David Schlessinger,Georg Schlieper,Marc A. Seelen,A. R. Shuldiner,Marketa Sjögren,J.H. Smit,Harold Snieder,Nicola Soranzo,Tim D. Spector,Peter Stenvinkel,Michael J.E. Sternberg,R. Swaminathan,L.J. Ubink-Veltmaat,Manuela Uda,Peter Vollenweider,Chris Wallace,Dawn M. Waterworth,Klaus Zerres,Gérard Waeber,Nicholas J. Wareham,Patrick H. Maxwell,Mark I. McCarthy,M-R Jarvelin,Vincent Mooser,G. Abecasis,Liz Lightstone,Jemima Scott,Gerjan Navis,Paul Elliott,Anna Köttgen,C. Pattaro,Carsten A. Böger,Christian Fuchsberger,Matthias Olden,Nicole L. Glazer,X. Gao,Qiong Yang,Albert V. Smith,Jeffery R. O'Connell,Man Li,H. Schmidt,A Isaacs,Shamika Ketkar,Shih-Jen Hwang,Andrew D. Johnson,Abbas Dehghan,A. Teumer,Guillaume Paré,Elizabeth J. Atkinson,Tanja Zeller,Kurt Lohman,Marilyn C. Cornelis,Nicole Probst-Hensch,Florian Kronenberg,A Tönjes,Caroline Hayward,Thor Aspelund,G. Eiriksdottir,L. J. Launer,T.B. Harris,Evandine Rampersaud,B. D. Mitchell,D.E. Arking,Eric Boerwinkle,Maksim Struchalin,Margherita Cavalieri,AB Singleton,Francesco Giallauria,Jeffrey Metter,I. H. de Boer,Talin Haritunians,Thomas Lumley,David S. Siscovick,Bruce M. Psaty,M. C. Zillikens,B.A. Oostra,Mary F. Feitosa,M. A. Province,M. De Andrade,Stephen T. Turner,Arne Schillert,Anette-G. Ziegler,Philipp S. Wild,Renate B. Schnabel,Sandra Wilde,Thomas Münzel,Tennille S. Leak,Thomas Illig,N. Klopp,Christine Meisinger,Heinz Erich Wichmann,Wolfgang Koenig,Lina Zgaga,Tatijana Zemunik,Ivana Kolcic,Cosetta Minelli,Frank B. Hu,Johansson,Wilmar Igl,Ghazal Zaboli,Sarah H. Wild,A. F. Wright,Hannah Campbell,David Ellinghaus,Stuart L. Schreiber,Y S Aulchenko,Janine F. Felix,F. Rivadeneira,A.G. Uitterlinden,A. Hofman,Medea Imboden,Dorothea Nitsch,Anita Brandstätter,Barbara Kollerits,Lyudmyla Kedenko,Reedik Mägi,Michael Stumvoll,Peter Kovacs,Mladen Boban,Sharon Campbell,Karlhans Endlich,Henry Völzke,Heyo K. Kroemer,Matthias Nauck,Uwe Völker,Ozren Polašek,Veronique Vitart,Sunita Badola,Alex Parker,Paul M. Ridker,Sharon L.R. Kardia,Stefan Blankenberg,Yongmei Liu,G. C. Curhan,Andre Franke,Tatiana Rochat,B. Paulweber,W. Wang,Vilmundur Gudnason,Josef Coresh,Reinhold E. Schmidt,Michael G. Shlipak,C M van Duijn,Ingrid B. Borecki,Bernhard K. Krämer,Igor Rudan,Ulf Gyllensten,J.F. Wilson,J. C. M. Witteman,Peter P. Pramstaller,Rainer Rettig,Nicholas D. Hastie,Daniel I. Chasman,W. H. Kao,I. M. Heid,Caroline S. Fox,Jan Krumsiek,Claudia Hundertmark,Giorgio Pistis,Daniela Ruggiero,M. O'seaghdha,T. Haller,Z. Kutalik,Julia Shi,P. S. Middelberg,Angelo L. Gaffo,Nicola Pirastu,Guo Li,Jennifer E. Huffman,Loic Yengo,Jing Hua Zhao,Ayse Demirkan,M. F. Feitosa,Xuan Liu,Giovanni Malerba,Lorna M. Lopez,Xinzhong Li,Marcus E. Kleber,Andrew A. Hicks,Ilja M. Nolte,Åsa Johansson,Federico Murgia,J F Peden,Maristella Steri,Albert Tenesa,Perttu Salo,Massimo Mangino,Lynda M. Rose,Terho Lehtimäki,Owen M. Woodward,Adrienne Tin,Craig Muller,Christopher Oldmeadow,Margus Putku,Darina Czamara,Peter Kraft,Laura Frogheri,Gian Andri Thun,Anne Grotevendt,Gauti Kjartan Gislason,Patrick F. McArdle,Michael Schallert,N. G. Martin,Grant W. Montgomery,David R. Jacobs,Kiang Liu,Pio D'Adamo,S. Ulivi,Jerome I. Rotter,P. Navaro,B. Balkau,Philippe Froguel,Tõnu Esko,Andres Salumets,Kay-Tee Khaw,Claudia Langenberg,Aldi T. Kraja,Qunyuan Zhang,Rodney J. Scott,Elizabeth G. Holliday,Elin Org,Margus Viigimaa,Stefania Bandinelli,Jeffery Metter,Antonio Lupo,Elisabetta Trabetti,Rossella Sorice,Angela Döring,Eva Lattka,Konstantin Strauch,Fabian J. Theis,M. Waldenberger,G. Davies,Alan J. Gow,Marcel Bruinenberg,Ronald P. Stolk,Winkelmann Br,B O Boehm,Susanne Lucae,G. Curhan,Poorva Mudgal,Robert M. Plenge,Laura Portas,Ivana Persico,Mirna Kirin,I. Mateo Leach,W. H. Van Gilst,Anuj Goel,Halit Ongen,A. von Eckardstein,Francesco Cucca,Ramaiah Nagaraja,Maria Grazia Piras,Claudia Schurmann,Klemens Budde,Florian Ernst,Susan M. Farrington,Evropi Theodoratou,A. Jula,M. Perola,V. Salomaa,So-Youn Shin,Cinzia Sala,Mika Kähönen,Jorma Viikari,Christian Hengstenberg,Christopher P. Nelson,James F. Meschia,Michael A. Nalls,Pankaj Sharma,Andrew B. Singleton,Michel Burnier,John Attia,Maris Laan,Hans L. Hillege,Stefan Kloiber,Hyon K. Choi,Mario Pirastu,Silvia Tore,John Whitfield,Myriam Fornage,Paolo Gasparini,David S. Siscovick,Nabila Bouatia-Naji,Andres Metspalu,Ingrid B. Borecki,Giovanni Gambaro,Ian J. Deary,Bruce H. R. Wolffenbuttel,W. März,Hugh Watkins,Sabine Schipf,Malcolm G. Dunlop,S. Ripatti,Daniela Toniolo,Olli T. Raitakari,Marina Ciullo,Mark J. Caulfield,C Gieger +414 more
TL;DR: A meta-analysis of genome-wide association studies for kidney function–related traits, including 71,149 east Asian individuals from 18 studies in 11 population-, hospital- or family-based cohorts, conducted as part of the Asian Genetic Epidemiology Network (AGEN), identified 17 loci newly associated with kidney function-related traits.