M
Minyoung Lee
Researcher at Virginia Commonwealth University
Publications - 9
Citations - 1020
Minyoung Lee is an academic researcher from Virginia Commonwealth University. The author has contributed to research in topics: Genome-wide association study & Anxiety. The author has an hindex of 8, co-authored 9 publications receiving 822 citations.
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Journal ArticleDOI
Meta-analysis of genome-wide association studies of anxiety disorders.
Takeshi Otowa,Takeshi Otowa,Karin Hek,Minyoung Lee,Enda M. Byrne,Enda M. Byrne,Saira Saeed Mirza,Michel G. Nivard,Timothy B. Bigdeli,Steven H. Aggen,Daniel E. Adkins,Aaron R. Wolen,Ayman H. Fanous,Ayman H. Fanous,Matthew C. Keller,Enrique Castelao,Zoltán Kutalik,Zoltán Kutalik,Zoltán Kutalik,S. V. der Auwera,Georg Homuth,Matthias Nauck,Alexander Teumer,Yuri Milaneschi,Yuri Milaneschi,Jouke-Jan Hottenga,Jouke-Jan Hottenga,Nese Direk,Albert Hofman,André G. Uitterlinden,Cornelis L. Mulder,Anjali K. Henders,Anjali K. Henders,Sarah E. Medland,Scott D. Gordon,A. C. Heath,P. A. F. Madden,Michele L. Pergadia,Michele L. Pergadia,P. J. van der Most,Ilja M. Nolte,F. V. A. van Oort,Catharina A. Hartman,Albertine J. Oldehinkel,Martin Preisig,Hans-Jörgen Grabe,Christel M. Middeldorp,Christel M. Middeldorp,Brenda W.J.H. Penninx,Dorret I. Boomsma,Nicholas G. Martin,Grant W. Montgomery,Brion S. Maher,E J C G van den Oord,Naomi R. Wray,Naomi R. Wray,Henning Tiemeier,Henning Tiemeier,John M. Hettema +58 more
TL;DR: To identify genetic variants contributing to genetic susceptibility shared across interview-generated DSM-based ADs, two phenotypic approaches were applied: (1) comparisons between categorical AD cases and supernormal controls, and (2) quantitative Phenotypic factor scores derived from a multivariate analysis combining information across the clinical phenotypes.
Journal ArticleDOI
Meta-analysis of Genome-wide Association Studies for Neuroticism, and the Polygenic Association With Major Depressive Disorder
Marleen H. M. de Moor,Stéphanie Martine van den Berg,Karin J. H. Verweij,Karin J. H. Verweij,Robert F. Krueger,Michelle Luciano,Alejandro Arias Vasquez,Lindsay K. Matteson,Jaime Derringer,Tõnu Esko,Najaf Amin,Scott D. Gordon,Narelle K. Hansell,Amy B. Hart,Ilkka Seppälä,Jennifer E. Huffman,Bettina Konte,Jari Lahti,Minyoung Lee,Michael B. Miller,Teresa Nutile,Toshiko Tanaka,Alexander Teumer,Alexander Viktorin,Juho Wedenoja,Gonçalo R. Abecasis,Daniel E. Adkins,Arpana Agrawal,Jüri Allik,Jüri Allik,Katja Appel,Timothy B. Bigdeli,Fabio Busonero,Harry Campbell,Paul T. Costa,George Davey Smith,Gail Davies,Harriet de Wit,Jun Ding,Barbara E. Engelhardt,Johan G. Eriksson,Iryna O. Fedko,Luigi Ferrucci,Barbara Franke,Ina Giegling,Richard A. Grucza,Annette M. Hartmann,Andrew C. Heath,Kati Heinonen,Anjali K. Henders,Georg Homuth,Jouke-Jan Hottenga,William G. Iacono,Joost G. E. Janzing,Markus Jokela,Robert Karlsson,John P. Kemp,John P. Kemp,Matthew G. Kirkpatrick,Antti Latvala,Antti Latvala,Terho Lehtimäki,David C. Liewald,Pamela A. F. Madden,Chiara Magri,Patrik K. E. Magnusson,Jonathan Marten,Andrea Maschio,Sarah E. Medland,Evelin Mihailov,Yuri Milaneschi,Grant W. Montgomery,Matthias Nauck,Klaasjan G. Ouwens,Aarno Palotie,Aarno Palotie,Erik Pettersson,Ozren Polasek,Yong Qian,Laura Pulkki-Råback,Olli T. Raitakari,Anu Realo,Richard J. Rose,Daniela Ruggiero,Carsten Oliver Schmidt,Wendy S. Slutske,Rossella Sorice,John M. Starr,Beate St Pourcain,Angelina R. Sutin,Angelina R. Sutin,Nicholas J. Timpson,Holly Trochet,Sita H. Vermeulen,Eero Vuoksimaa,Elisabeth Widen,Jasper Wouda,Jasper Wouda,Margaret J. Wright,Lina Zgaga,Lina Zgaga,David J. Porteous,Alessandra Minelli,Abraham A. Palmer,Dan Rujescu,Marina Ciullo,Caroline Hayward,Igor Rudan,Andres Metspalu,Jaakko Kaprio,Jaakko Kaprio,Ian J. Deary,Katri Räikkönen,James F. Wilson,Liisa Keltikangas-Järvinen,Laura J. Bierut,John M. Hettema,Hans Joergen Grabe,Cornelia M. van Duijn,David M. Evans,David M. Evans,David Schlessinger,N. L. Pedersen,Antonio Terracciano,Matt McGue,Matt McGue,Brenda W.J.H. Penninx,Nicholas G. Martin,Dorret I. Boomsma +128 more
TL;DR: This study identifies a novel locus for neuroticism located in a known gene that has been associated with bipolar disorder and schizophrenia in previous studies and shows that neuroticism is influenced by many genetic variants of small effect that are either common or tagged by common variants.
Journal ArticleDOI
Meta-analysis of Genome-Wide Association Studies for Extraversion: Findings from the Genetics of Personality Consortium
Stéphanie Martine van den Berg,Marleen H. M. de Moor,Karin J. H. Verweij,Karin J. H. Verweij,Robert F. Krueger,Michelle Luciano,Alejandro Arias Vasquez,Lindsay K. Matteson,Jaime Derringer,Tõnu Esko,Najaf Amin,Scott D. Gordon,Narelle K. Hansell,Amy B. Hart,Ilkka Seppälä,Jennifer E. Huffman,Bettina Konte,Jari Lahti,Minyoung Lee,Michael B. Miller,Teresa Nutile,Toshiko Tanaka,Alexander Teumer,Alexander Viktorin,Juho Wedenoja,Abdel Abdellaoui,Gonçalo R. Abecasis,Daniel E. Adkins,Arpana Agrawal,Jueri Allik,Jueri Allik,Katja Appel,Timothy B. Bigdeli,Fabio Busonero,Harry Campbell,Paul T. Costa,George Davey Smith,Gail Davies,Harriet de Wit,Jun Ding,Barbara E. Engelhardt,Johan G. Eriksson,Iryna O. Fedko,Luigi Ferrucci,Barbara Franke,Ina Giegling,Richard A. Grucza,Annette M. Hartmann,Andrew C. Heath,Kati Heinonen,Anjali K. Henders,Georg Homuth,Jouke-Jan Hottenga,William G. Iacono,Joost G. E. Janzing,Markus Jokela,Robert Karlsson,John P. Kemp,John P. Kemp,Matthew G. Kirkpatrick,Antti Latvala,Antti Latvala,Terho Lehtimäki,David C. Liewald,Pamela A. F. Madden,Chiara Magri,Patrik K. E. Magnusson,Jonathan Marten,Andrea Maschio,Hamdi Mbarek,Sarah E. Medland,Evelin Mihailov,Yuri Milaneschi,Grant W. Montgomery,Matthias Nauck,Michel G. Nivard,Klaasjan G. Ouwens,Aarno Palotie,Aarno Palotie,Erik Pettersson,Ozren Polasek,Yong Qian,Laura Pulkki-Råback,Olli T. Raitakari,Olli T. Raitakari,Anu Realo,Richard J. Rose,Daniela Ruggiero,Carsten Oliver Schmidt,Wendy S. Slutske,Rossella Sorice,John M. Starr,Beate St Pourcain,Angelina R. Sutin,Angelina R. Sutin,Nicholas J. Timpson,Holly Trochet,Sita H. Vermeulen,Eero Vuoksimaa,Elisabeth Widen,Jasper Wouda,Jasper Wouda,Margaret J. Wright,Lina Zgaga,Lina Zgaga,David J. Porteous,Alessandra Minelli,Abraham A. Palmer,Dan Rujescu,Marina Ciullo,Caroline Hayward,Igor Rudan,Andres Metspalu,Andres Metspalu,Jaakko Kaprio,Jaakko Kaprio,Ian J. Deary,Katri Räikkönen,James F. Wilson,James F. Wilson,Liisa Keltikangas-Järvinen,Laura J. Bierut,John M. Hettema,Hans J. Grabe,Brenda W.J.H. Penninx,Cornelia M. van Duijn,David M. Evans,David Schlessinger,Nancy L. Pedersen,Antonio Terracciano,Matt McGue,Matt McGue,Nicholas G. Martin,Dorret I. Boomsma +133 more
TL;DR: A large meta-analysis of GWA studies for extraversion in 63,030 subjects in 29 cohorts shows that extraversion is a highly polygenic personality trait, with an architecture possibly different from other complex human traits, including other personality traits.
Journal ArticleDOI
Erratum: Meta-analysis of genome-wide association studies of anxiety disorders (vol 21, pg 1391, 2016)
Takeshi Otowa,Karin Hek,Minyoung Lee,Enda M. Byrne,Saira Saeed Mirza,Michel G. Nivard,Timothy B. Bigdeli,Steven H. Aggen,Daniel E. Adkins,Aaron R. Wolen,Ayman H. Fanous,Matthew C. Keller,Enrique Castelao,Z. Kutalik,S. V. der Auwera,Georg Homuth,Matthias Nauck,A. Teumer,Y. Milaneschi,J-J Hottenga,Nese Direk,A. Hofman,A.G. Uitterlinden,Cornelis L. Mulder,Anjali K. Henders,S. E. Medland,Scott D. Gordon,A. C. Heath,P. A. F. Madden,M. L. Pergadia,P. J. van der Most,Ilja M. Nolte,F. V. A. van Oort,C.A. Hartman,Albertine J. Oldehinkel,Martin Preisig,Hans-Jörgen Grabe,Christel M. Middeldorp,B.W.J.H. Penninx,D.I. Boomsma,Nicholas G. Martin,Grant W. Montgomery,Brion S. Maher,E. J. C. G. van den Oord,N. R. Wray,Henning Tiemeier,John M. Hettema +46 more
TL;DR: The fifteenth author's name was presented incorrectly and the author’s name should have appeared as S Van der Auwera and the publisher regrets the error.
Journal ArticleDOI
Generalised Anxiety Disorder – A Twin Study of Genetic Architecture, Genome-Wide Association and Differential Gene Expression
Matthew N. Davies,Serena Verdi,Andrea Burri,Maciej Trzaskowski,Minyoung Lee,John M. Hettema,Rick Jansen,Dorret I. Boomsma,Tim D. Spector +8 more
TL;DR: A genome-wide association study of AS using a cohort of 730 MZ and DZ female twins showed a significant association for a variant within the RBFOX1 gene, which suggests a novel etiology specific to AS.