P
Patoomratana Tuchinda
Researcher at Mahidol University
Publications - 180
Citations - 3222
Patoomratana Tuchinda is an academic researcher from Mahidol University. The author has contributed to research in topics: Nucleophilic addition & Enantioselective synthesis. The author has an hindex of 28, co-authored 175 publications receiving 2783 citations. Previous affiliations of Patoomratana Tuchinda include University of Illinois at Chicago.
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Journal ArticleDOI
Evaluation of the mutagenic, cytotoxic, and antitumor potential of triptolide, a highly oxygenated diterpene isolated from Tripterygium wilfordii
Lisa A. Shamon,John M. Pezzuto,J. M. Graves,Rajeshwari R. Mehta,Sirichai Wangcharoentrakul,Ranee Sangsuwan,Suttiporn Chaichana,Patoomratana Tuchinda,Per Cleason,Vichai Reutrakul +9 more
TL;DR: Tripterygium wilfordii Hook f. (Celastraceae) has been shown to demonstrate potent antileukemic activity in rodent models at remarkably low treatment doses.
Journal ArticleDOI
Anti-inflammatory cyclohexenyl chalcone derivatives in Boesenbergia pandurata.
Patoomratana Tuchinda,Vichai Reutrakul,P. Claeson,U. Pongprayoon,T. Sematong,Thawatchai Santisuk,Walter C. Taylor +6 more
TL;DR: The cyclohexenyl chalcone derivative and (-)-panduratin A showed significant topical anti-inflammatory activity in the assay of TPA-induced ear edema in rats.
Journal ArticleDOI
Plant anticancer agents, XLVIII. New cytotoxic flavonoids from Muntingia calabura roots.
Norito Kaneda,John M. Pezzuto,Djaja D. Soejarto,A. Douglas Kinghorn,Norman R. Farnsworth,T. Santisuk,Patoomratana Tuchinda,Jinda Udchachon,Vichai Reutrakul +8 more
TL;DR: Most of the isolates demonstrated cytotoxic activity when tested against cultured P-388 cells, with the flavans being more active than the flavones, and certain of these structurally related flavonoids exhibited somewhat selective activities when evaluated with a number of human cancer cell lines.
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High-content screening of Thai medicinal plants reveals Boesenbergia rotunda extract and its component Panduratin A as anti-SARS-CoV-2 agents.
Phongthon Kanjanasirirat,Ampa Suksatu,Suwimon Manopwisedjaroen,Bamroong Munyoo,Patoomratana Tuchinda,Kedchin Jearawuttanakul,Sawinee Seemakhan,Sitthivut Charoensutthivarakul,Patompon Wongtrakoongate,Noppawan Rangkasenee,Supaporn Pitiporn,Neti Waranuch,Napason Chabang,Phisit Khemawoot,Khanit Sa-ngiamsuntorn,Yongyut Pewkliang,Piyanoot Thongsri,Somchai Chutipongtanate,Suradej Hongeng,Suparerk Borwornpinyo,Arunee Thitithanyanont +20 more
TL;DR: It is demonstrated, for the first time, that panduratin A exerts the inhibitory effect against SARS-CoV-2 infection at both pre-entry and post-infection phases.
Journal ArticleDOI
Cytotoxic and anti-HIV-1 caged xanthones from the resin and fruits of Garcinia hanburyi.
Vichai Reutrakul,Natthinee Anantachoke,Manat Pohmakotr,Thaworn Jaipetch,Samaisukh Sophasan,Chalobon Yoosook,Jittra Kasisit,Chanita Napaswat,Thawatchai Santisuk,Patoomratana Tuchinda +9 more
TL;DR: This work represents the first report on the anti-HIV-1 activities of caged xanthones.