P
Patrick Neubert
Researcher at University Hospital Regensburg
Publications - 15
Citations - 591
Patrick Neubert is an academic researcher from University Hospital Regensburg. The author has contributed to research in topics: Periodontal fiber & Bone remodeling. The author has an hindex of 7, co-authored 15 publications receiving 423 citations. Previous affiliations of Patrick Neubert include University of Erlangen-Nuremberg.
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Journal ArticleDOI
Cutaneous Na(+) storage strengthens the antimicrobial barrier function of the skin and boosts macrophage-driven host defense
Jonathan Jantsch,Jonathan Jantsch,Valentin Schatz,Valentin Schatz,Diana Friedrich,Agnes Schröder,Christoph W. Kopp,Isabel Siegert,Andreas Maronna,David Wendelborn,Peter Linz,Katrina J. Binger,Matthias Gebhardt,Matthias Heinig,Matthias Heinig,Patrick Neubert,Fabian Fischer,Stefan Teufel,Stefan Teufel,Jean-Pierre David,Jean-Pierre David,Clemens Neufert,Alexander Cavallaro,Natalia Rakova,Christoph Küper,F. X. Beck,Wolfgang Neuhofer,Dominik N. Müller,Gerold Schuler,Michael Uder,Christian Bogdan,Friedrich C. Luft,Friedrich C. Luft,Jens Titze,Jens Titze +34 more
TL;DR: It is suggested that the hypertonic microenvironment could serve as a barrier to infection and increase Na(+) content in the skin by a high-salt diet boosted activation of macrophages in a Nfat5-dependent manner and promoted cutaneous antimicrobial defense.
Journal ArticleDOI
High salt intake reprioritizes osmolyte and energy metabolism for body fluid conservation
Kento Kitada,Steffen Daub,Yahua Zhang,Janet D. Klein,Daisuke Nakano,Tetyana V. Pedchenko,Louise Lantier,Lauren M. LaRocque,Adriana Marton,Patrick Neubert,Agnes Schröder,Natalia Rakova,Jonathan Jantsch,Anna Dikalova,Sergey Dikalov,David G. Harrison,Dominik N. Müller,Akira Nishiyama,Manfred Rauh,Raymond C. Harris,Friedrich C. Luft,David H. Wasserman,Jeff M. Sands,Jens Titze +23 more
TL;DR: It is demonstrated that urine concentration, and therefore regulation of water conservation, is an important control system for urine formation and extracellular volume homeostasis in mice and humans across various levels of salt intake.
Journal ArticleDOI
Elementary immunology: Na + as a regulator of immunity
Valentin Schatz,Patrick Neubert,Agnes Schröder,Katrina J. Binger,Matthias Gebhard,Dominik N. Müller,Friedrich C. Luft,Friedrich C. Luft,Jens Titze,Jens Titze,Jonathan Jantsch +10 more
TL;DR: It is demonstrated that local Na+ availability is a promising novel regulator of immunity and may help in treating infections, while lowering tissue Na+ levels may be used to treat autoimmune and cardiovascular diseases.
Journal ArticleDOI
Na+ deposition in the fibrotic skin of systemic sclerosis patients detected by 23Na-magnetic resonance imaging.
Christoph W. Kopp,Christian Beyer,Peter Linz,Anke Dahlmann,Matthias Hammon,Jonathan Jantsch,Patrick Neubert,Daniela Rosenhauer,Dominik N. Müller,Alexander Cavallaro,Kai-Uwe Eckardt,Georg Schett,Friedrich C. Luft,Friedrich C. Luft,Michael Uder,Jörg H W Distler,Jens Titze +16 more
TL;DR: These findings provide the first evidence that 23Na‐MRI might be a promising tool to assess skin Na+ and thereby predict progression of skin fibrosis in SSc.
Journal ArticleDOI
A high-salt diet compromises antibacterial neutrophil responses through hormonal perturbation.
Katarzyna Jobin,Natascha E. Stumpf,Sebastian Schwab,Melanie Eichler,Patrick Neubert,Manfred Rauh,Marek Adamowski,Olena Babyak,Daniel Hinze,Sugirthan Sivalingam,Christina Weisheit,Katharina Hochheiser,Susanne Schmidt,Mirjam Meissner,Natalio Garbi,Zeinab Abdullah,Ulrich Wenzel,Michael Hölzel,Jonathan Jantsch,Christian Kurts +19 more
TL;DR: These findings argue against high-salt consumption during bacterial infections, and reveal that people might be making themselves more vulnerable to bacterial infections.