P
Paul Milligan
Researcher at University of London
Publications - 196
Citations - 11162
Paul Milligan is an academic researcher from University of London. The author has contributed to research in topics: Malaria & Population. The author has an hindex of 59, co-authored 190 publications receiving 10174 citations. Previous affiliations of Paul Milligan include University of Liverpool & University of Salford.
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Journal ArticleDOI
Efficacy of RTS, S/AS02 malaria vaccine against Plasmodium falciparum infection in semi-immune adult men in The Gambia: a randomised trial
Kalifa Bojang,Paul Milligan,Margaret Pinder,Laurence Vigneron,Ali Alloueche,Kent E. Kester,W. Ripley Ballou,David J. Conway,William H. H. Reece,Philip Gothard,Lawrence Yamuah,Martine Delchambre,Gerald Voss,Brian Greenwood,Adrian V. S. Hill,Keith P. W. J. McAdam,Nadia Tornieporth,Joe Cohen,Tom Doherty +18 more
TL;DR: RTS,S/AS02 is safe, immunogenic, and is the first pre-erythrocytic vaccine to show significant protection against natural P. falciparum infection in semi-immune adult men in The Gambia.
Journal ArticleDOI
Bulletin of the World Health Organization
Marianne A B van der Sande,G. Walraven,Paul Milligan,Winston A. S. Banya,S. M. Ceesay,Ousman Nyan,Keith P. W. J. McAdam +6 more
TL;DR: A family history of hypertension, obesity, diabetes, or stroke was a significant risk factor for obesity and hyperlipidaemia in adults in the Gambia, and health professionals should utilize every opportunity to include direct family members in health education.
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Elimination of Haemophilus influenzae type b (Hib) disease from The Gambia after the introduction of routine immunisation with a Hib conjugate vaccine: a prospective study
Richard A. Adegbola,Ousman Secka,George Lahai,Nellie Lloyd-Evans,Alpha Njie,Stanley Usen,Claire Oluwalana,Stephen K Obaro,Martin W. Weber,Tumani Corrah,Kim Mulholland,Keith P. W. J. McAdam,Brian Greenwood,Paul Milligan +13 more
TL;DR: The Gambian Hib immunisation programme reduced the occurrence of Hib disease despite irregular vaccine supply, and has important implications for the introduction of the vaccine into routine immunisation programmes of other developing countries.
Journal ArticleDOI
A CD4(+) T-cell immune response to a conserved epitope in the circumsporozoite protein correlates with protection from natural Plasmodium falciparum infection and disease.
William H. H. Reece,Margaret Pinder,Philip Gothard,Paul Milligan,Kalifa Bojang,Tom Doherty,Magdalena Plebanski,Peter Akinwunmi,Simone Everaere,Katherine R Watkins,Gerald Voss,Nadia Tornieporth,Ali Alloueche,Brian Greenwood,Kent E. Kester,Keith P. W. J. McAdam,Joe Cohen,Adrian V. S. Hill +17 more
TL;DR: A peptide-specific T-cell assay that is strongly associated with protection of humans in The Gambia, West Africa, from both malaria infection and disease is reported, providing direct evidence for a protective role for CD4+ T cells in humans.
Journal ArticleDOI
Artesunate Reduces but Does Not Prevent Posttreatment Transmission of Plasmodium falciparum to Anopheles gambiae
Geoffrey A. T. Targett,Chris Drakeley,Musa Jawara,Lorenz von Seidlein,Rosalind Coleman,J L Deen,Margaret Pinder,Tom Doherty,Tom Doherty,Colin J. Sutherland,Gijs Walraven,Paul Milligan +11 more
TL;DR: Questions are raised about any policy to use pyrimethamine-sulfadoxine alone as the first-line treatment for malaria, and the effect of such therapy on transmission is examined.