P
Paul Telfer
Researcher at Queen Mary University of London
Publications - 117
Citations - 4006
Paul Telfer is an academic researcher from Queen Mary University of London. The author has contributed to research in topics: Anemia & Sickle cell anemia. The author has an hindex of 29, co-authored 106 publications receiving 3224 citations. Previous affiliations of Paul Telfer include Royal London Hospital & National Health Service.
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Journal ArticleDOI
Controlled trial of transfusions for silent cerebral infarcts in sickle cell anemia
Michael R. DeBaun,Mae O. Gordon,Robert C. McKinstry,Michael J. Noetzel,Desirée A. White,Sharada A. Sarnaik,Emily Riehm Meier,Thomas H. Howard,Suvankar Majumdar,Baba Inusa,Paul Telfer,Melanie Kirby-Allen,Timothy L. McCavit,Annie Kamdem,Gladstone Airewele,Gerald M. Woods,Brian Berman,Julie A. Panepinto,Beng Fuh,Janet L. Kwiatkowski,Allison A. King,Jason Fixler,Melissa Rhodes,Alexis A. Thompson,Mark E. Heiny,Rupa Redding-Lallinger,Fenella J. Kirkham,Natalia Dixon,Corina E. Gonzalez,Karen Kalinyak,Charles T. Quinn,John J. Strouse,J. P. Miller,Harold P Lehmann,Michael A. Kraut,William S. Ball,Deborah Hirtz,James F. Casella +37 more
TL;DR: Regular blood-transfusion therapy significantly reduced the incidence of the recurrence of cerebral infarct in children with sickle cell anemia.
Journal ArticleDOI
A Phase 3 Randomized Trial of Voxelotor in Sickle Cell Disease
Elliott Vichinsky,Carolyn Hoppe,Kenneth I. Ataga,Russell E. Ware,Videlis Nduba,Amal El-Beshlawy,Hoda Hassab,Maureen Achebe,Salam Alkindi,R. Clark Brown,David L. Diuguid,Paul Telfer,Dimitris A. Tsitsikas,Ashraf Elghandour,Victor R. Gordeuk,Julie Kanter,Miguel R. Abboud,Joshua Lehrer-Graiwer,Margaret Tonda,Allison Intondi,Barbara Tong,Jo Howard +21 more
TL;DR: Voxelotor significantly increased hemoglobin levels and reduced markers of hemolysis in this phase 3 randomized, placebo-controlled trial involving participants with sickle cell disease, consistent with inhibition of HbS polymerization and indicate a disease-modifying potential.
Journal ArticleDOI
Clinical outcomes in children with sickle cell disease living in England: a neonatal cohort in East London
Paul Telfer,Pietro G Coen,Subarna Chakravorty,O Wilkey,Jane P. M. Evans,Heather Newell,Beverley Smalling,Roger J Amos,Adrian D. Stephens,David W. Rogers,Fenella J. Kirkham +10 more
TL;DR: Mortality in childhood SCD can virtually be eliminated in a well-resourced health service setting linking community-based care with a specialized, hospital-based center.
Journal ArticleDOI
Guidelines for the management of the acute painful crisis in sickle cell disease
TL;DR: These guidelines aim to provide advice on a basic, minimum standard of care for patients with acute painful crises and SCD, and pay particular attention to adequate analgesia and monitoring for life-threatening complications.
Journal ArticleDOI
Survival of medically treated thalassemia patients in Cyprus. Trends and risk factors over the period 1980-2004
Paul Telfer,Pietro G Coen,Soteroula Christou,Michael Hadjigavriel,Anita Kolnakou,Evangelia Pangalou,Nicos Pavlides,Michael Psiloines,Krikor Simamonian,Georghios Skordos,Maria Sitarou,Michael Angastiniotis +11 more
TL;DR: Most patients born after 1974 survive to at least the age of 30 and there has been a marked improvement in survival for patients of all ages since 2000, which may be due to the introduction of combination chelation therapy.