P
Peter M. Rothwell
Researcher at University of Oxford
Publications - 815
Citations - 77220
Peter M. Rothwell is an academic researcher from University of Oxford. The author has contributed to research in topics: Stroke & Population. The author has an hindex of 134, co-authored 779 publications receiving 67382 citations. Previous affiliations of Peter M. Rothwell include Leicester Royal Infirmary & University of Edinburgh.
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Journal ArticleDOI
Change in stroke incidence, mortality, case-fatality, severity, and risk factors in Oxfordshire, UK from 1981 to 2004 (Oxford Vascular Study)
Peter M. Rothwell,A J Coull,Matthew F. Giles,Sally C. Howard,Louise E. Silver,Linda M. Bull,Sergei A. Gutnikov,Phil Edwards,David Mant,Catherine Sackley,Andrew Farmer,Pag Sandercock,Dennis,Charles Warlow,John Bamford,P Anslow +15 more
TL;DR: The age-specific incidence of major stroke in Oxfordshire has fallen by 40% over the past 20 years in association with increased use of preventive treatments and major reductions in premorbid risk factors.
Journal ArticleDOI
Effect of urgent treatment of transient ischaemic attack and minor stroke on early recurrent stroke (EXPRESS study): a prospective population-based sequential comparison.
Peter M. Rothwell,Matthew F. Giles,Arvind Chandratheva,Lars Marquardt,Olivia C. Geraghty,Jessica Redgrave,Caroline E. Lovelock,L E Binney,Linda M. Bull,Fiona C. Cuthbertson,Sarah J.V. Welch,Shelley Bosch,Faye Carasco-Alexander,Louise E. Silver,Sergei A. Gutnikov,Ziyah Mehta +15 more
TL;DR: In this article, the effect of more rapid treatment after transient ischaemic attack (TIA) and minor stroke in patients who are not admitted direct to hospital was investigated. But the results were limited to patients with TIA or minor stroke not admitted directly to hospital.
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Population-based study of event-rate, incidence, case fatality, and mortality for all acute vascular events in all arterial territories (Oxford Vascular Study)
Peter M. Rothwell,A J Coull,Louise E. Silver,J. F. Fairhead,Matthew F. Giles,Caroline E. Lovelock,Jne Redgrave,Linda M. Bull,Sjv Welch,Fiona C. Cuthbertson,L E Binney,Sergei A. Gutnikov,P Anslow,Adrian P. Banning,David Mant,Ziyah Mehta +15 more
TL;DR: The high rates of acute vascular events outside the coronary arterial territory and the steep rise in event rates with age in all territories have implications for prevention strategies, clinical trial design, and the targeting of funds for service provision and research.
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Subgroup analysis in randomised controlled trials: importance, indications, and interpretation
TL;DR: Subgroup analyses are important if there are potentially large differences between groups in the risk of a poor outcome with or without treatment, if there is potential heterogeneity of treatment effect in relation to pathophysiology, or ifthere are practical questions about when to treat.
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Effect of daily aspirin on risk of cancer metastasis: a study of incident cancers during randomised controlled trials
TL;DR: It is suggested that aspirin might help in treatment of some cancers and provides proof of principle for pharmacological intervention specifically to prevent distant metastasis in patients who developed cancer during trials of daily aspirin versus control.