P
Peter M. Rothwell
Researcher at University of Oxford
Publications - 815
Citations - 77220
Peter M. Rothwell is an academic researcher from University of Oxford. The author has contributed to research in topics: Stroke & Population. The author has an hindex of 134, co-authored 779 publications receiving 67382 citations. Previous affiliations of Peter M. Rothwell include Leicester Royal Infirmary & University of Edinburgh.
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Journal ArticleDOI
Modelling the distribution of white matter hyperintensities due to ageing on MRI images using Bayesian inference.
Vaanathi Sundaresan,Ludovica Griffanti,Petya Kindalova,Fidel Alfaro-Almagro,Giovanna Zamboni,Peter M. Rothwell,Thomas E. Nichols,Mark Jenkinson +7 more
TL;DR: The proposed Bayesian spline method models the spatio‐temporal distribution of WMH with respect to a parametric factor of interest, in this case age, within a population, and finds that the overall probability of lesions is significantly higher in later age groups, which is in line with the current literature.
Journal ArticleDOI
Reporting of consistency of blood pressure control in randomized controlled trials of antihypertensive drugs: a systematic review of 1372 trial reports.
TL;DR: Reporting of BP control is limited in RCTs of BP-lowering drugs, particularly given that inconsistent control is associated with a high risk of stroke and that antihypertensive drug classes differ in this regard.
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Blood pressure-lowering treatment for prevention of major cardiovascular diseases in people with and without type 2 diabetes: an individual participant-level data meta-analysis
Milad Nazarzadeh,Zeinab Bidel,Dexter Canoy,Emma Copland,Derrick A Bennett,Abbas Dehghan,George Davey Smith,Rury R. Holman,Mark Woodward,Ajay Gupta,Amanda I Adler,Malgorzata Wamil,Naveed Sattar,William C. Cushman,Richard J McManus,K. Teo,Barry R. Davis,John Chalmers,Carl J. Pepine,Kazem Rahimi,Lawrence Y. Agodoa,Ale Algra,Folkert W. Asselbergs,N Beckett,Eivind Berge,Henry R. Black,Frank P. Brouwers,M. Brown,Christopher J. Bulpitt,Bob Byington,J E Cutler,Richard B. Devereux,John Dwyer,Raymond O. Estacio,R. H. Fagard,K K Fox,Takeshi Fukui,Yutaka Imai,Misaki Ishii,Stevo Julius,Yoshihiko Kanno,S.E. Kjeldsen,John B. Kostis,K. Kuramoto,Jan Lanke,Edmund J. Lewis,J. Lewis,M. Lievre,Lars H Lindholm,Stephan Lueders,Stephen MacMahon,Giuseppe Mancia,M. Matsuzaki,Maria H Mehlum,S. Nissen,Hisao Ogawa,Tsutomu Ogihara,Tomihiko Ohkubo,C. Palmer,Anushka Patel,Melanie Pfeffer,Neil R Poulter,Hiromi Rakugi,Gianpaolo Reboldi,Christopher M. Reid,Giuseppe Remuzzi,Piero Ruggenenti,Toshihisa Saruta,J Schrader,Robert W. Schrier,Peter S. Sever,Peter Sleight,Jan A. Staessen,Hiromichi Suzuki,L. Thijs,Kazuaki Ueshima,Seiji Umemoto,Wiek H. van Gilst,Paolo Verdecchia,Kristian Wachtell,Paul K. Whelton,Lindon M H Wing,Yoshida Yui,SM Taslim Yusuf,Alberto Zanchetti,Z. Zhang,C. Anderson,Colin Baigent,B. Brenner,R Collins,Dick de Zeeuw,Jacobus Lubsen,Ettore Malacco,Bruce Neal,Vlado Perkovic,Brendan Pitt,Anthony Rodgers,Peter M. Rothwell,Gholamreza Salimi-Khorshidi,Jessica Sundström,Fiona Turnbull,Giancarlo Viberti,J. Wang +102 more
Journal ArticleDOI
Vertebral artery stenting to prevent recurrent stroke in symptomatic vertebral artery stenosis: the VIST RCT.
Hugh S. Markus,Susanna C. Larsson,John Dennis,Wilhelm Küker,Ursula G. Schulz,Ian Ford,Andrew Clifton,Peter M. Rothwell +7 more
TL;DR: The Vertebral artery Ischaemia Stenting Trial was established to compare the risks and benefits of vertebral angioplasty and stenting with best medical treatment (BMT) alone for recently symptomatic VA stenosis and found no difference in risk of the primary end point between the two groups.
Journal ArticleDOI
Genetics of the thrombomodulin-endothelial cell protein C receptor system and the risk of early-onset ischemic stroke
John W. Cole,Huichun Xu,Kathleen A. Ryan,Thomas Jaworek,Nicole Dueker,Patrick F. McArdle,Brady Gaynor,Yu-Ching Cheng,Jeffrey R. O'Connell,Steve Bevan,Rainer Malik,Naveed Uddin Ahmed,Philippe Amouyel,Sheraz Anjum,Joshua C. Bis,David R. Crosslin,John Danesh,Stefan T. Engelter,Myriam Fornage,Philippe M. Frossard,Christian Gieger,Anne-Katrin Giese,Caspar Grond-Ginsbach,Weang Kee Ho,Elizabeth G. Holliday,Jemma C. Hopewell,Muzaffar Hussain,W Iqbal,Sehrish Jabeen,Jim Jannes,Ayeesha Kamran Kamal,Yoichiro Kamatani,Sandip M. Kanse,Manja Kloss,Mark Lathrop,Didier Leys,Arne Lindgren,William T. Longstreth,Khalid Mahmood,Christa Meisinger,Tiina M. Metso,Thomas H. Mosley,Martina Müller-Nurasyid,Bo Norrving,Eugenio Parati,Annette Peters,Alessandro Pezzini,I Quereshi,Asif Rasheed,A Rauf,T Salam,J. Shen,Agnieszka Slowik,Tara M. Stanne,Konstantin Strauch,Turgut Tatlisumak,Vincent Thijs,Steffen Tiedt,Matthew Traylor,Melanie Waldenberger,Matthew Walters,Wei Zhao,Giorgio B. Boncoraglio,Stéphanie Debette,Christina Jern,Christopher R Levi,Hugh S. Markus,James F. Meschia,Arndt Rolfs,Peter M. Rothwell,Danish Saleheen,Sudha Seshadri,Pankaj Sharma,Cathie Sudlow,Bradford B. Worrall,O. Colin Stine,Steven J. Kittner,Braxton D. Mitchell +77 more
TL;DR: Polymorphisms in the endothelial-based receptors of the thrombomodulin−protein C system (THBD and PROCR) may similarly be associated with early-onset ischemic stroke and associations were strengthened among those without risk factors.