P
Peter M. Rothwell
Researcher at University of Oxford
Publications - 815
Citations - 77220
Peter M. Rothwell is an academic researcher from University of Oxford. The author has contributed to research in topics: Stroke & Population. The author has an hindex of 134, co-authored 779 publications receiving 67382 citations. Previous affiliations of Peter M. Rothwell include Leicester Royal Infirmary & University of Edinburgh.
Papers
More filters
Journal ArticleDOI
Age-stratified and blood-pressure-stratified effects of blood-pressure-lowering pharmacotherapy for the prevention of cardiovascular disease and death: an individual participant-level data meta-analysis
Kazem Rahimi,Zeinab Bidel,Milad Nazarzadeh,Emma Copland,Dexter Canoy,Malgorzata Wamil,Jeannette Majert,Richard J McManus,Amanda I Adler,Larry Agodoa,Ale Algra,Folkert W. Asselbergs,N Beckett,Eivind Berge,Henry R. Black,Eric Boersma,Frank P. Brouwers,Morris J. Brown,Jasper J Brugts,Christopher J. Bulpitt,Robert P Byington,William C. Cushman,Jeffrey Cutler,Richard B Devereaux,Jamie P. Dwyer,Ray Estacio,Robert Fagard,Kim Fox,Tsuguya Fukui,Ajay Gupta,Rury R. Holman,Yutaka Imai,Masao Ishii,Stevo Julius,Yoshihiko Kanno,Sverre E. Kjeldsen,John B. Kostis,Kizuku Kuramoto,Jan Lanke,Edmund J. Lewis,Julia B. Lewis,Michel Lievre,Lars H Lindholm,Stephan Lueders,Stephen MacMahon,Giuseppe Mancia,Masunori Matsuzaki,Maria H Mehlum,Steven E. Nissen,Hiroshi Ogawa,Toshio Ogihara,Takayoshi Ohkubo,Christopher R. Palmer,Anushka Patel,MA Pfeffer,Bertram Pitt,Neil R Poulter,Hiromi Rakugi,Gianpaolo Reboldi,Christopher M. Reid,Giuseppe Remuzzi,Piero Ruggenenti,Takao Saruta,Joachim Schrader,Robert W. Schrier,Peter S. Sever,Peter Sleight,Jan A. Staessen,Hiromichi Suzuki,Lutgarde Thijs,Kenji Ueshima,Seiji Umemoto,Wiek H. van Gilst,Paolo Verdecchia,Kristian Wachtell,Paul K. Whelton,Lindon Wing,Mark Woodward,Yoshiki Yui,Salim Yusuf,Alberto Zanchetti,Zhen-Yu Zhang,Craig S. Anderson,Colin Baigent,Barry M. Brenner,Rory Collins,Dick de Zeeuw,Jacobus Lubsen,Ettore Malacco,Bruce Neal,Vlado Perkovic,Anthony Rodgers,Peter M. Rothwell,Gholamreza Salimi-Khorshidi,Johan Sundström,Fiona Turnbull,Giancarlo Viberti,Ji-Guang Wang,John Chalmers,Barry R. Davis,Carl J. Pepine,Koon K. Teo +101 more
TL;DR: Pharmacological blood pressure reduction is effective into old age, with no evidence that relative risk reductions for prevention of major cardiovascular events vary by systolic or diastolic blood pressure levels at randomisation, down to less than 120/70 mm Hg.
Journal ArticleDOI
Risk and treatment effect heterogeneity: re-analysis of individual participant data from 32 large clinical trials.
David M. Kent,Jason Nelson,Issa J Dahabreh,Peter M. Rothwell,Douglas G. Altman,Rodney A. Hayward +5 more
TL;DR: There is typically substantial variation in outcome risk in clinical trials, commonly leading to clinically significant differences in absolute treatment effects most patients have outcome risks lower than the trial average reflected in the summary result.
Reference EntryDOI
Patches of different types for carotid patch angioplasty
TL;DR: There is some evidence that other synthetic (e.g. PTFE) patches may be superior to collagen impregnated Dacron grafts in terms of perioperative stroke rates and restenosis, but more trial data is required to establish whether any differences do exist.
Journal ArticleDOI
Multicenter randomized study of anticoagulation guided by remote rhythm monitoring in patients with implantable cardioverter-defibrillator and CRT-D devices: Rationale, design, and clinical characteristics of the initially enrolled cohort : The IMPACT study
John Ip,Albert L. Waldo,Gregory Y.H. Lip,Peter M. Rothwell,David Martin,Malcolm M. Bersohn,Wassim K Choucair,Joseph G. Akar,Mark S. Wathen,Pooyan Rohani,Jonathan L. Halperin +10 more
TL;DR: The results will help define the clinical utility of wireless remote cardiac rhythm surveillance and help establish the critical threshold of AHRE burden warranting anticoagulant therapy in patients at risk of stroke.
Journal ArticleDOI
Common variation in COL4A1/COL4A2 is associated with sporadic cerebral small vessel disease.
Kristiina Rannikmäe,Gail Davies,Pippa A. Thomson,Steve Bevan,William J. Devan,Guido J. Falcone,Matthew Traylor,Christopher D. Anderson,Thomas W.K. Battey,Farid Radmanesh,Ranjan Deka,Jessica G. Woo,Lisa J. Martin,Jordi Jimenez-Conde,Magdy Selim,Devin L. Brown,Scott Silliman,Chelsea S. Kidwell,Joan Montaner,Carl D. Langefeld,Agnieszka Slowik,Björn M. Hansen,Arne Lindgren,James F. Meschia,Myriam Fornage,Joshua C. Bis,Stéphanie Debette,Mohammad Arfan Ikram,Will Longstreth,Reinhold Schmidt,Cathy R. Zhang,Qiong Yang,Pankaj Sharma,Steven J. Kittner,Braxton D. Mitchell,Elizabeth G. Holliday,Christopher R Levi,John Attia,Peter M. Rothwell,D Poole,Giorgio B. Boncoraglio,Bruce M. Psaty,Rainer Malik,Natalia S. Rost,Bradford B. Worrall,Martin Dichgans,Tom Van Agtmael,Daniel Woo,Hugh S. Markus,Sudha Seshadri,Jonathan Rosand,Cathie Sudlow +51 more
TL;DR: The results indicate an association between common variation in the COL4A2 gene and symptomatic small vessel disease, particularly deep intracerebral hemorrhage, and merit replication studies, including in ethnic groups of non-European ancestry.