Peter M. Rothwell

TL;DR: The early risk of recurrence after transient ischaemic attack (TIA) or minor stroke is high, ranging from 11% at 7 days in population-based studies, where patients are seen non-urgently, to 3% in studies where patients were seen urgently in specialist services, whereas the risk of coronary events is constant over the follow-up period at around 2% per year as discussed by the authors.

TL;DR: Primary studies should distinguish ipsilateral from contralateral arteries and carefully describe the patients' characteristics and study environment to inform physicians in routine clinical practice.

TL;DR: About 70% of patients do not correctly recognize their TIA or minor stroke, 30% delay seeking medical attention for >24 hours, regardless of age, sex, social class, or educational level, and approximately 30% of early recurrent strokes occur before seeking attention.

TL;DR: A novel association on chromosome 12q24 (rs10744777, odds ratio [OR] 1.10 [1.07–1.13], p = 7.12 × 10−11) was identified with ischemic stroke rather than an individual stroke subtype, with similar effect sizes seen in different stroke subtypes.

TL;DR: There was no difference in the risk of death/stroke relative to the timing of CEA (pre- versus on-cardiopulmonary bypass), but recent small studies indicate that improved outcomes might be achieved by performing CABG 'off-bypass'.